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CD46 Antibody

CD46 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCD46
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IF, WB, IHC
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the CD46 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis CD46 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P15529
PurityAntigen affinity
Description Finally, In addition, The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system, and type IV pili of pathogenic Neisseria, human herpesvirus-6, the encoded protein can act as a receptor for the Edmonston strain of measles virus, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization, which protects the host cell from damage by complement, CD46 is a type I membrane protein and is a regulatory part of the complement system
ImmunogenA portion of amino acids 317-343 from the human protein was used as the immunogen for this CD46 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CD46 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCD46
Short nameCD46 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name complement regulatory protein (Antibody to), CD46 molecule
Alternative techniqueantibodies
Alternative to gene target AHUS2 and MCP and MIC10 and TLX and TRA2, BT, CD46 and IDBG-106372 and ENSG00000117335 and 4179, Cd46 and IDBG-209330 and ENSMUSG00000016493 and 17221, Cell surfaces, cadherin binding, classical pathway and biological process this GO :0007338 and single fertilization and biological process this GO :0008593 and regulation of Notch signaling pathway and biological process this GO :0009986 and cell surface and cellular component this GO :0010628 and positive regulation of gene expression and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0016032 and viral process and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0032613 and interleukin-10 production and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0035581 and sequestering of extracellular ligand from receptor and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0043382 and positive regulation of memory T cell differentiation and biological process this GO :0045087 and innate immune response and biological process this GO :0045296 and cadherin binding and molecular function this GO :0045591 and positive regulation of regulatory T cell differentiation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071636 and positive regulation of transforming growth factor beta production and biological process, complement regulatory protein, this GO :0002079 and inner acrosomal membrane and cellular component this GO :0002250 and adaptive immune response and biological process this GO :0002456 and T cell mediated immunity and biological process this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006958 and complement activation, this GO :0004872: receptor activity, this GO :0004872: receptor activity and also this GO :0005515: protein binding and also this GO :0045296: cadherin binding, this GO :0005515: protein binding, this GO :0045296: cadherin binding, 10, 68611 and IDBG-638462 and ENSBTAG00000005397 and 280851, CD46 molecule
Identity 6953
Gene CD46
Long gene name CD46 molecule
Synonyms gene MIC10 MCP
Synonyms gene name antigen identified by monoclonal antibody TRA-2-10 membrane cofactor protein (CD46, complement regulatory protein , complement regulatory protein CD46 molecule, trophoblast-lymphocyte cross-reactive antigen) CD46 antigen
Synonyms TRA2, 10 MGC26544 TLX
Locus 1q32, 2
Discovery year 1988-08-31
GenBank acession BC030594
Entrez gene record 4179
Pubmed identfication 7929741
RefSeq identity NM_172361
Classification Sushi domain containing Complement system CD molecules
Havana BLAST/BLAT OTTHUMG00000036397
Locus Specific Databases LRG_155

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