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CD46/MCP Antibody, Biotin Conjugated

CD46/MCP Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, CD46/MCP Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCD46/MCP
SpecificityThis is a highly specific antibody against CD46/MCP
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range250-300/365
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from Mouse CD46
Gene ID number4179
Swiss ProtP15529
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityMouse
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46, Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells, May be involved in the fusion of the spermatozoa with the oocyte during fertilization, T-regulatory 1 cells suppress immune responses by secreting interleukin-10, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue, and therefore are thought to prevent autoimmunity, Acts as a cofactor for complement factor I
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms TRA2, 10 MGC26544 TLX
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCD46/MCP Conjugated
Short name Conjugated, CD46/MCP Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, complement regulatory protein/MCP (Antibody to), CD46 molecule
Alternative techniqueantibodies
Alternative to gene target AHUS2 and MCP and MIC10 and TLX and TRA2, BT, CD46 and IDBG-106372 and ENSG00000117335 and 4179, Cd46 and IDBG-209330 and ENSMUSG00000016493 and 17221, Cell surfaces, cadherin binding, classical pathway and biological process this GO :0007338 and single fertilization and biological process this GO :0008593 and regulation of Notch signaling pathway and biological process this GO :0009986 and cell surface and cellular component this GO :0010628 and positive regulation of gene expression and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0016032 and viral process and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0032613 and interleukin-10 production and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0035581 and sequestering of extracellular ligand from receptor and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0043382 and positive regulation of memory T cell differentiation and biological process this GO :0045087 and innate immune response and biological process this GO :0045296 and cadherin binding and molecular function this GO :0045591 and positive regulation of regulatory T cell differentiation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071636 and positive regulation of transforming growth factor beta production and biological process, complement regulatory protein, this GO :0002079 and inner acrosomal membrane and cellular component this GO :0002250 and adaptive immune response and biological process this GO :0002456 and T cell mediated immunity and biological process this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006958 and complement activation, this GO :0004872: receptor activity, this GO :0004872: receptor activity and also this GO :0005515: protein binding and also this GO :0045296: cadherin binding, this GO :0005515: protein binding, this GO :0045296: cadherin binding, 10, 68611 and IDBG-638462 and ENSBTAG00000005397 and 280851, CD46 molecule
Identity 6953
Gene CD46
Long gene name CD46 molecule
Synonyms gene MIC10 MCP
Synonyms gene name antigen identified by monoclonal antibody TRA-2-10 membrane cofactor protein (CD46, complement regulatory protein , complement regulatory protein CD46 molecule, trophoblast-lymphocyte cross-reactive antigen) CD46 antigen
Locus 1q32, 2
Discovery year 1988-08-31
GenBank acession BC030594
Entrez gene record 4179
Pubmed identfication 7929741
RefSeq identity NM_172361
Classification Sushi domain containing Complement system CD molecules
Havana BLAST/BLAT OTTHUMG00000036397
Locus Specific Databases LRG_155

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