Filters

CD46/MCP Antibody, PE Conjugated

CD46/MCP Antibody, PE Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name PE Conjugated, CD46/MCP Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationPE
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCD46/MCP
SpecificityThis is a highly specific antibody against CD46/MCP
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range250-300/365
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from Mouse CD46
Gene ID number4179
Swiss ProtP15529
Tested applicationsFCM
Recommended dilutionsFCM(1:20-100)
CrossreactivityMouse
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46, Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells, May be involved in the fusion of the spermatozoa with the oocyte during fertilization, T-regulatory 1 cells suppress immune responses by secreting interleukin-10, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue, and therefore are thought to prevent autoimmunity, Acts as a cofactor for complement factor I
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission480, 565nm/578nm
Synonyms TRA2, 10 MGC26544 TLX
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCD46/MCP PE Conjugated
Short name PE Conjugated, CD46/MCP Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelPE
Alternative name complement regulatory protein/MCP (Antibody to), peroxidase coupled, CD46 molecule
Alternative techniqueantibodies
Alternative to gene target AHUS2 and MCP and MIC10 and TLX and TRA2, BT, CD46 and IDBG-106372 and ENSG00000117335 and 4179, Cd46 and IDBG-209330 and ENSMUSG00000016493 and 17221, Cell surfaces, cadherin binding, classical pathway and biological process this GO :0007338 and single fertilization and biological process this GO :0008593 and regulation of Notch signaling pathway and biological process this GO :0009986 and cell surface and cellular component this GO :0010628 and positive regulation of gene expression and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0016032 and viral process and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0032613 and interleukin-10 production and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0035581 and sequestering of extracellular ligand from receptor and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0043382 and positive regulation of memory T cell differentiation and biological process this GO :0045087 and innate immune response and biological process this GO :0045296 and cadherin binding and molecular function this GO :0045591 and positive regulation of regulatory T cell differentiation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071636 and positive regulation of transforming growth factor beta production and biological process, complement regulatory protein, this GO :0002079 and inner acrosomal membrane and cellular component this GO :0002250 and adaptive immune response and biological process this GO :0002456 and T cell mediated immunity and biological process this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006958 and complement activation, this GO :0004872: receptor activity, this GO :0004872: receptor activity and also this GO :0005515: protein binding and also this GO :0045296: cadherin binding, this GO :0005515: protein binding, this GO :0045296: cadherin binding, 10, 68611 and IDBG-638462 and ENSBTAG00000005397 and 280851, CD46 molecule
Identity 6953
Gene CD46
Long gene name CD46 molecule
Synonyms gene MIC10 MCP
Synonyms gene name antigen identified by monoclonal antibody TRA-2-10 membrane cofactor protein (CD46, complement regulatory protein , complement regulatory protein CD46 molecule, trophoblast-lymphocyte cross-reactive antigen) CD46 antigen
Locus 1q32, 2
Discovery year 1988-08-31
GenBank acession BC030594
Entrez gene record 4179
Pubmed identfication 7929741
RefSeq identity NM_172361
Classification Sushi domain containing Complement system CD molecules
Havana BLAST/BLAT OTTHUMG00000036397
Locus Specific Databases LRG_155

Similar products

Subscribe to our Newsletter