Name : CD47/MER6 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5430817374
| Long name | CD47/MER6 Primary Polyclonal Antibody |
| Also known as | CD47/MER6 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CD47/MER6 |
| Specificity | This is a highly specific antibody against CD47/MER6 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 280-323/323 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD47/MER6 |
| Gene ID number | 961 |
| Swiss Prot | Q08722 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Interaction with SIRPG mediates cell-cell adhesion, May be involved in membrane permeability changes induced following virus infection, May play a role in membrane transport and/or integrin dependent signal transduction, May prevent premature elimination of red blood cells, Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity), Receptor for SIRPA, and in the modulation of integrins, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation, Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Antigenic surface determinant protein OA3, CD47, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, OA3, Protein MER6, IAP |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CD47/MER6 |
| Short name | CD47/MER6 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD47 molecule/MER6 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CD47 and IDBG-48744 and ENSG00000196776 and 961, CD47 and IDBG-631689 and ENSBTAG00000003585 and 282661, Cd47 and IDBG-165137 and ENSMUSG00000055447 and 16423, IAP and MER6 and OA3, Plasma membranes, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0008228 and opsonization and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009617 and response to bacterium and biological process this GO :0022409 and positive regulation of cell-cell adhesion and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0050900 and leukocyte migration and biological process this GO :0070053 and thrombospondin receptor activity and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0070053: thrombospondin receptor activity, this GO :0070053: thrombospondin receptor activity, thrombospondin receptor activity, CD47 molecule |
| Identity | 1682 |
| Gene | CD47 |
| Long gene name | CD47 molecule |
| Synonyms gene | MER6 |
| Synonyms gene name | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) |
| Synonyms | IAP OA3 |
| Synonyms name | antigen identified by monoclonal antibody 1D8 antigenic surface determinant protein OA3 integrin associated protein Rh-related antigen leukocyte surface antigen CD47 CD47 glycoprotein |
| Locus | 3q13, 12 |
| Discovery year | 1994-12-12 |
| Entrez gene record | 961 |
| Pubmed identfication | 8294396 2277087 |
| RefSeq identity | NM_001777 |
| Classification | Immunoglobulin like domain containing CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000044216 |