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CD47/MER6 Antibody, Biotin Conjugated

CD47/MER6 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, CD47/MER6 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCD47/MER6
SpecificityThis is a highly specific antibody against CD47/MER6
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range280-323/323
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human CD47/MER6
Gene ID number961
Swiss ProtQ08722
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Interaction with SIRPG mediates cell-cell adhesion, May be involved in membrane permeability changes induced following virus infection, May play a role in membrane transport and/or integrin dependent signal transduction, May prevent premature elimination of red blood cells, Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity), Receptor for SIRPA, and in the modulation of integrins, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation, Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms IAP OA3
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCD47/MER6 Conjugated
Short name Conjugated, CD47/MER6 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, CD47 molecule/MER6 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CD47 and IDBG-48744 and ENSG00000196776 and 961, CD47 and IDBG-631689 and ENSBTAG00000003585 and 282661, Cd47 and IDBG-165137 and ENSMUSG00000055447 and 16423, IAP and MER6 and OA3, Plasma membranes, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0008228 and opsonization and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009617 and response to bacterium and biological process this GO :0022409 and positive regulation of cell-cell adhesion and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0050900 and leukocyte migration and biological process this GO :0070053 and thrombospondin receptor activity and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0070053: thrombospondin receptor activity, this GO :0070053: thrombospondin receptor activity, thrombospondin receptor activity, CD47 molecule
Identity 1682
Gene CD47
Long gene name CD47 molecule
Synonyms gene MER6
Synonyms gene name CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
Synonyms name antigen identified by monoclonal antibody 1D8 antigenic surface determinant protein OA3 integrin associated protein Rh-related antigen leukocyte surface antigen CD47 CD47 glycoprotein
Locus 3q13, 12
Discovery year 1994-12-12
Entrez gene record 961
Pubmed identfication 8294396 2277087
RefSeq identity NM_001777
Classification Immunoglobulin like domain containing CD molecules
Havana BLAST/BLAT OTTHUMG00000044216

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