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CD58 Antibody / LFA3

CD58 Antibody / LFA3 size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCD58 / LFA3
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions1-0, 5-1ug/ml, 5ug/ml, IHC (FFPE): 0, Western blot: 0
NotesOptimal dilution of the CD58 antibody should be determined by the researcher
Intented useThis CD58 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P19256
PurityAntigen affinity
Description It binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells, The LFA3 gene is mapped to chromosome 1p13, This adhesion occurs as part of the transitory initial encounters between T cells and Antigen Presenting Cells before T cell activation, is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), or lymphocyte function-associated antigen 3 (LFA-3), particularly macrophages, when T cells are roaming the lymph nodes looking at the surface of APCs for peptide:MHC complexes the T-cell receptors are reactive to, which is the same location as CD2, CD58
ImmunogenAmino acids F29-R215 from the human protein were used as the immunogen for the CD58 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CD58 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
Localization cell surface, Cytoplasmic
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCD58 / LFA3
Short nameCD58 Antibody / LFA3
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCD58 molecule (Antibody to) / LFA3
Alternative techniqueantibodies
Alternative to gene target CD58 and IDBG-101394 and ENSG00000116815 and 965, CD58 and IDBG-634482 and ENSBTAG00000040131 and 782186, Cell surfaces, ag3 and LFA-3 and LFA3, protein binding, this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007596 and blood coagulation and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0031225 and anchored component of membrane and cellular component this GO :0034113 and heterotypic cell-cell adhesion and biological process this GO :0050900 and leukocyte migration and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071346 and cellular response to interferon-gamma and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :2000484 and positive regulation of interleukin-8 secretion and biological process, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005515: protein binding, this GO :0005515: protein binding, CD58 molecule
Identity 1688
Gene CD58
Long gene name CD58 molecule
Synonyms gene LFA3
Synonyms gene name (lymphocyte function-associated antigen 3) , CD58 antigen
Locus 1p13, 1
Discovery year 1989-04-06
GenBank acession BC005930
Entrez gene record 965
Pubmed identfication 9510189
RefSeq identity NM_001779
Classification CD molecules
Havana BLAST/BLAT OTTHUMG00000022749

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