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CD95 (Tyr291) Antibody

CD95 (Tyr291) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCD95 (Tyr291) Primary Polyclonal Antibody
Also known asCD95 (Tyr291) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCD95 Tyr291
SpecificityThis is a highly specific antibody against CD95 Tyr291
Modification(s)Phosphorylation
Modification site(s)Tyr291
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human FAS around the phosphorylation site of Tyr291
Gene ID number355
Swiss ProtP25445
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, The adapter molecule FADD recruits caspase-8 to the activated receptor, The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis, The secreted isoforms 2 to 6 block apoptosis (in vitro), in the antigen-stimulated suicide of mature T-cells, or both, Receptor for TNFSF6/FASLG
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ALPS1A, APO-1, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6, Tumor necrosis factor receptor superfamily member 6, APT1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCD95 (Tyr291)
Short nameCD95 (Tyr291) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCD95 (Tyr291) (Antibody to)
Alternative techniqueantibodies
Identity 11920
Gene FAS
Long gene name Fas cell surface death receptor
Synonyms gene FAS1 APT1 TNFRSF6
Synonyms gene name member 6 Fas (TNF receptor superfamily, member 6) , tumor necrosis factor receptor superfamily
Synonyms CD95 APO-1
Synonyms name TNF receptor superfamily member 6
Locus 10q23, 31
Discovery year 1992-06-25
GenBank acession M67454
Entrez gene record 355
Pubmed identfication 1385299 1385309
Classification CD molecules Tumor necrosis factor receptor superfamily Death inducing signaling complex
Havana BLAST/BLAT OTTHUMG00000018701
Locus Specific Databases Autoimmune Lymphoproliferative Syndrome Database (ALPSbase): Database of mutations causing human ALPS LOVD at NCBI LRG_134

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