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CD95 (Tyr291) Antibody, Biotin Conjugated

CD95 (Tyr291) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, CD95 (Tyr291) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCD95 Tyr291
SpecificityThis is a highly specific antibody against CD95 Tyr291
ModificationPhosphorylation
Modification siteTyr291
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human FAS around the phosphorylation site of Tyr291
Gene ID number355
Swiss ProtP25445
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, The adapter molecule FADD recruits caspase-8 to the activated receptor, The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis, The secreted isoforms 2 to 6 block apoptosis (in vitro), in the antigen-stimulated suicide of mature T-cells, or both, Receptor for TNFSF6/FASLG
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms CD95 APO-1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCD95 (Tyr291) Conjugated
Short name Conjugated, CD95 (Tyr291) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, CD95 (Tyr291) (Antibody to)
Alternative techniqueantibodies
Identity 11920
Gene FAS
Long gene name Fas cell surface death receptor
Synonyms gene FAS1 APT1 TNFRSF6
Synonyms gene name member 6 Fas (TNF receptor superfamily, member 6) , tumor necrosis factor receptor superfamily
Synonyms name TNF receptor superfamily member 6
Locus 10q23, 31
Discovery year 1992-06-25
GenBank acession M67454
Entrez gene record 355
Pubmed identfication 1385299 1385309
Classification CD molecules Tumor necrosis factor receptor superfamily Death inducing signaling complex
Havana BLAST/BLAT OTTHUMG00000018701
Locus Specific Databases Autoimmune Lymphoproliferative Syndrome Database (ALPSbase): Database of mutations causing human ALPS LOVD at NCBI LRG_134

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