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CD95 (Tyr291) Antibody, FITC Conjugated

CD95 (Tyr291) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, CD95 (Tyr291) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCD95 Tyr291
SpecificityThis is a highly specific antibody against CD95 Tyr291
ModificationPhosphorylation
Modification siteTyr291
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human FAS around the phosphorylation site of Tyr291
Gene ID number355
Swiss ProtP25445
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, The adapter molecule FADD recruits caspase-8 to the activated receptor, The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis, The secreted isoforms 2 to 6 block apoptosis (in vitro), in the antigen-stimulated suicide of mature T-cells, or both, Receptor for TNFSF6/FASLG
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms CD95 APO-1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCD95 (Tyr291) Conjugated
Short name FITC Conjugated, CD95 (Tyr291) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, CD95 (Tyr291) (Antibody to)
Alternative techniqueantibodies
Identity 11920
Gene FAS
Long gene name Fas cell surface death receptor
Synonyms gene FAS1 APT1 TNFRSF6
Synonyms gene name member 6 Fas (TNF receptor superfamily, member 6) , tumor necrosis factor receptor superfamily
Synonyms name TNF receptor superfamily member 6
Locus 10q23, 31
Discovery year 1992-06-25
GenBank acession M67454
Entrez gene record 355
Pubmed identfication 1385299 1385309
Classification CD molecules Tumor necrosis factor receptor superfamily Death inducing signaling complex
Havana BLAST/BLAT OTTHUMG00000018701
Locus Specific Databases Autoimmune Lymphoproliferative Syndrome Database (ALPSbase): Database of mutations causing human ALPS LOVD at NCBI LRG_134

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