| Long name | CD98 Primary Polyclonal Antibody |
| Also known as | CD98 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CD98 |
| Specificity | This is a highly specific antibody against CD98 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 257-280/630 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD98 |
| Gene ID number | 6520 |
| Swiss Prot | P08195 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane, Involved in sodium-independent, Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D, Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine, Required for normal and neoplastic cell growth, Together with ICAM1, When associated with SLC7A5, When associated with SLC7A5 or SLC7A8, When associated with SLC7A5/LAT1, When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, and hence plays a role in metal ion homeostasis and toxicity, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta, arginine and tryptophan, by generating and delivering intracellular signals, following an antiport mechanism for amino acid transport, high-affinity transport of large neutral amino acids such as phenylalanine, influencing arginine release in exchange for extracellular amino acids, involved in the cellular activity of small molecular weight nitrosothiols, is also involved in the transport of L-DOPA across the blood-brain barrier, leucine, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier, regulates the transport activity LAT2 in polarized intestinal cells, tyrosine, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane, L-homocysteine complexes, Required for the function of light chain amino-acid transporters |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 4F2 cell-surface antigen heavy chain, 4F2 heavy chain antigen, 4F2HC, 4T2HC, CD98, CD98HC, Lymphocyte activation antigen 4F2 large subunit, MDU1, NACAE, SLC3A2, Solute carrier family 3 member 2, 4F2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CD98 |
| Short name | CD98 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD98 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11063 |
| Gene | SLC7A5 |
| Long gene name | solute carrier family 7 member 5 |
| Synonyms gene name | L system), member 5 , solute carrier family 7 (amino acid transporter light chain |
| Synonyms | LAT1 E16 D16S469E MPE16 CD98 |
| Locus | 16q24, 2 |
| Discovery year | 1999-01-28 |
| GenBank acession | AF077866 |
| Entrez gene record | 8140 |
| Pubmed identfication | 9751058 7829099 |
| RefSeq identity | NM_003486 |
| Classification | Solute carriers CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000137658 |
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