Filters

Cdc14A Antibody

Cdc14A Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCdc14A Primary Polyclonal Antibody
Also known asCdc14A PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCdc14A
SpecificityThis is a highly specific antibody against Cdc14A
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Cdc14A
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Cdc14a dephosphorylates hCdh1 and activates APCCdh1, Cdc14a phosphatase plays a role in the regulation of the centrosome cycle, Deregulated human Cdc14a phosphatase disrupts centrosome separation and chromosome segregation, Human Cdc14a phosphatase is highly similar to Saccharomyces cerevisiae Cdc14 and is a member of the dual specificity protein Tyrosine phosphatase family, In addition, It interacts with and dephosphorylates tumor suppressor protein p53 and may regulate the function of p53, mitosis and cytokinesis, the Cdc14a phosphatase activates mitotic exit by dephosphorylation of specific cyclin-dependent kinase (Cdk) substrates and seems to be regulated by sequestration in the nucleolus until its release during mitosis, thereby influencing chromosome partitioning and genomic stability in human cells, In budding yeast
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CC14A_HUMAN, CDC10, CDC14 cell division cycle 14 homolog A, CDC14 homolog A, Cdc 14, Cdc 14A, Cdc 14A1, Cdc 14A2, Cdc14, Cdc14A1, Cdc14A2, Cell division cycle 14 homolog A, Dual specicity protein phosphatase CDC 14A, Dual specicity protein phosphatase CDC14A, hCDC14, CDC 10
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCdc14A
Short nameCdc14A Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCdc14A (Antibody to)
Alternative techniqueantibodies
Identity 1718
Gene CDC14A
Long gene name cell division cycle 14A
Synonyms gene name CDC10 (cell division cycle 10, S, cerevisiae, cerevisiae) , homolog) CDC14 cell division cycle 14 homolog A (S
Synonyms Cdc14A1 Cdc14A2 cdc14 DFNB105
Locus 1p21, 2
Discovery year 1998-12-18
GenBank acession AF000367
Entrez gene record 8556
Pubmed identfication 9367992 10409437 27259055
RefSeq identity NM_033312
Classification CDC14 phosphatases
Havana BLAST/BLAT OTTHUMG00000010987

Similar products

Subscribe to our Newsletter