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CDC16(Ser560) Antibody, Biotin Conjugated

CDC16(Ser560) Antibody, Biotin Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Biotin Conjugated, CDC16(Ser560) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCDC16 Ser560
SpecificityThis is a highly specific antibody against CDC16 Ser560
ModificationPhosphorylation
Modification siteSer560
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human APC6 around the phosphorylation site of Ser560
Gene ID number8881
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Cdc16 and Cdc27 are components of the APC (anaphase-promoting complex) which ubiquitinates cyclin B, Cdc25A, Cdc25B and Cdc25C protein tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory tyrosine residues, Cdc27 and Cdc16 function as ubiquitin-conjugating enzymes, Cdc34, Cdc34 is thought to be the structural and functional homolog of Saccharomyces cerevisiae Cdc34, Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with Hsp90, Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, The cell division cycle (Cdc) genes are required at various points in the cell cycle, resulting in cyclin B/Cdk complex degradation, which is essential for the G1 to S phase transition, which is involved in the initiation of DNA replication, Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms APC6 ANAPC6 CUT9
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCDC16(Ser560) Conjugated
Short name Conjugated, CDC16(Ser560) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, CDC16(Ser560) (Antibody to)
Alternative techniqueantibodies
Identity 1720
Gene CDC16
Long gene name cell division cycle 16
Synonyms gene name CDC16 (cell division cycle 16, S, cerevisiae, cerevisiae) , cerevisiae) cell division cycle 16 homolog (S, homolog) CDC16 cell division cycle 16 homolog (S
Synonyms name anaphase-promoting complex, subunit 6
Locus 13q34
Discovery year 1999-06-07
GenBank acession U18291
Entrez gene record 8881
Pubmed identfication 7736578
RefSeq identity NM_003903
Classification Anaphase promoting complex Tetratricopeptide repeat domain containing
Havana BLAST/BLAT OTTHUMG00000017402

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