| Long name | Cdc2 Primary Polyclonal Antibody |
| Also known as | Cdc2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Cdc25 |
| Specificity | This is a highly specific antibody against Cdc25 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Source | Recombinant human protein purified from E, coli(His-cdc2) |
| Gene ID number | 983 |
| Swiss Prot | P06493 |
| Tested Applications | IP, WB |
| Recommended dilutions | 000) IP (1 ul), WB (1:2 |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | A Cdk is activated by association with a cyclin, Cdk1, Cdk1, Cdk1 can also enhance cell migration, Cdks are also involved in the regulation of transcription and mRNA processing, Increased levels of Cdk1 promote cell migration together with cyclin B2 and the actin-stabilizing protein caldesmon, Phosphorylation of caldesmon bound to actin results in the displacement of caldesmon from actin followed by the altered interaction of actin with myosin, The Cdk1 protein is constantly present throughout the cell division cycle, These events contribute to increased cell migration, allows a dividing cell to enter into mitosis from G2 and permits the transition from G1 through S in conjunction with cyclin A and cyclin E, also known as cell division control protein 2 (cdc2), but its activity is finely tuned by means of protein-protein interactions and reversible phosphorylation, forming a cyclin-dependent kinase complex, is one of the components of the maturation promoting factor (MPF) which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle, when bound to cyclin B, Cyclin-dependent kinases (cdk) belong to a group of protein kinases originally discovered as being involved in the regulation of the cell cycle |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CDC28A, CDK1, CDKN1, Cell division control protein 2 homolog, Cell division protein kinase 1, Cyclin-dependent kinase 1, P34CDC2, p34 protein kinase, CDC2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Cdc2 |
| Short name | Cdc2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Cdc2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9175 |
| Gene | POLD1 |
| Long gene name | DNA polymerase delta 1, catalytic subunit |
| Synonyms gene | POLD |
| Synonyms gene name | catalytic subunit , catalytic subunit (125kD) polymerase (DNA) delta 1, delta 1, polymerase (DNA directed) |
| Synonyms | CDC2 |
| Synonyms name | CDC2 homolog (S, cerevisiae) |
| Locus | 19q13, 3 |
| Discovery year | 1992-02-06 |
| Entrez gene record | 5424 |
| Pubmed identfication | 1722322 |
| Classification | DNA polymerases |
| Havana BLAST/BLAT | OTTHUMG00000183037 |
| Locus Specific Databases | LRG_785 |
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