Filters

cdc2 (Thr14) Antibody, Cy7 Conjugated

cdc2 (Thr14) Antibody, Cy7 Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, cdc2 (Thr14) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigencdc2 Thr14
SpecificityThis is a highly specific antibody against cdc2 Thr14
ModificationPhosphorylation
Modification siteThr14
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human cdc2 around the phosphorylation site of Thr14 [EG(p-T)YG]
Gene ID number983
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161, Cdc2 exists as a complex with both cyclin A and cyclin B, Furthermore, However, Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase, The best characterized of these associations is the Cdc2 p34 cyclin B complex, The isoform CDC2deltaT is found in breast cancer tissues, also known as cyclin dependent kinase 1 (Cdk1) or p34/cdk1, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration, plays a key role in the control of the eukaryotic cell cycle, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14, where it is required for entry into S phase and mitosis, which is required for the G2 to M phase transition, The cell division control protein cdc2
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms CDK 1, CDK1, Cdc 2, Cell Divsion Cycle 2 Protein, Cell division control protein 2, Cell division control protein 2 homolog, Cell division cycle 2 G1 to S and G2 to M, P34CDC2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetcdc2 (Thr14) Conjugated
Short name Conjugated, cdc2 (Thr14) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, cdc2 (Thr14) (Antibody to)
Alternative techniqueantibodies

Similar products

Subscribe to our Newsletter