| Long name | 1, 3) Monoclonal Antibody, CDH1 (813CT11 |
| Also known as | 1, 3) Monoclonal Antibody, CDH1 (813CT11 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CDH1 |
| Specificity | This is a highly specific antibody against CDH1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 1, 3, 813CT11 |
| Source | Purified His-tagged CDH1 protein was used to produced this monoclonal antibody |
| Gene ID number | 999 |
| Swiss Prot | P12830 |
| Tested Applications | IHC-P, WB |
| Recommended dilutions | WB(1:1000), IHC-P(1:25) |
| Cross reactivity | Mouse, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | CDH1 is involved in mechanisms regulating cell-cell adhesions, E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors, Has a potent invasive suppressor role, Has a strong inhibitory effect on APP C99 and C83 production, It is a ligand for integrin alpha-E/beta-7, They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types, mobility and proliferation of epithelial cells, Cadherins are calcium-dependent cell adhesion proteins |
| Purification method | This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Arc-1, CAM 120/80, CD324, CDH1, CDHE, Cadherin-1, E-cadherin, ECAD, Epithelial cadherin, LCAM, Uvomorulin, UVO |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 1, 3) Monoclonal, CDH1 (813CT11 |
| Short name | 1, 3) Monoclonal Antibody, CDH1 (813CT11 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | E-cadherin (epithelial) (813CT11, classification 1, 1, 3) monoclonal (Antibody to), cadherin 1 |
| Alternative technique | antibodies |
| Alternative to gene target | Arc-1 and CD324 and CDHE and ECAD and LCAM and UVO, BT, CDH1 and IDBG-38622 and ENSG00000039068 and 999, Cdh1 and IDBG-190074 and ENSMUSG00000000303 and 12550, DNA-templated and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0050776 and regulation of immune response and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0051260 and protein homooli this GO merization and biological process this GO :0060576 and intestinal epithelial cell development and biological process this GO :0060662 and salivary gland cavitation and biological process this GO :0060693 and regulation of branching involved in salivary gland morphogenesis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070830 and tight junction assembly and biological process this GO :0071230 and cellular response to amino acid stimulus and biological process this GO :0071285 and cellular response to lithium ion and biological process this GO :0071681 and cellular response to indole-3-methanol and biological process this GO :0071944 and cell periphery and cellular component this GO :0072659 and protein localization to plasma membrane and biological process this GO :0090002 and establishment of protein localization to plasma membrane and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :0090102 and cochlea development and biological process this GO :2000008 and regulation of protein localization to cell surface and biological process this GO :2001222 and regulation of neuron migration and biological process, E-cadherin (epithelial), Extracellular, cell adhesion molecule binding, this GO :0001701 and in utero embryonic development and biological process this GO :0001829 and trophectodermal cell differentiation and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0003382 and epithelial cell morphogenesis and biological process this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005802 and trans- this GO lgi network and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005912 and adherens junction and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007416 and synapse assembly and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0009636 and response to toxic substance and biological process this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010033 and response to organic substance and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016235 and aggresome and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016328 and lateral plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0016339 and calcium-dependent cell-cell adhesion and biological process this GO :0016342 and catenin complex and cellular component this GO :0019538 and protein metabolic process and biological process this GO :0019903 and protein phosphatase binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0021983 and pituitary gland development and biological process this GO :0022408 and negative regulation of cell-cell adhesion and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030054 and cell junction and cellular component this GO :0030198 and extracellular matrix organization and biological process this GO :0030424 and axon and cellular component this GO :0030506 and ankyrin binding and molecular function this GO :0031175 and neuron projection development and biological process this GO :0032794 and GTPase activating protein binding and molecular function this GO :0032880 and regulation of protein localization and biological process this GO :0033268 and node of Ranvier and cellular component this GO :0033561 and regulation of water loss via skin and biological process this GO :0034329 and cell junction assembly and biological process this GO :0034332 and adherens junction organization and biological process this GO :0042493 and response to drug and biological process this GO :0042993 and positive regulation of transcription factor import into nucleus and biological process this GO :0043219 and lateral loop and cellular component this GO :0043220 and Schmidt-Lanterman incisure and cellular component this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043296 and apical junction complex and cellular component this GO :0043679 and axon terminus and cellular component this GO :0045177 and apical part of cell and cellular component this GO :0045216 and cell-cell junction organization and biological process this GO :0045295 and gamma-catenin binding and molecular function this GO :0045893 and positive regulation of transcription, this GO :0001948: glycoprotein binding, this GO :0001948: glycoprotein binding and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0008013: beta-catenin binding and also this GO :0019903: protein phosphatase binding and also this GO :0019904: protein domain specific binding and also this GO :0030506: ankyrin binding and also this GO :0032794: GTPase activating protein binding and also this GO :0045295: gamma-catenin binding and also this GO :0050839: cell adhesion molecule binding, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0008013: beta-catenin binding, this GO :0019903: protein phosphatase binding, this GO :0019904: protein domain specific binding, this GO :0030506: ankyrin binding, this GO :0032794: GTPase activating protein binding, this GO :0045295: gamma-catenin binding, this GO :0050839: cell adhesion molecule binding, type 1, 64827 and IDBG-634263 and ENSBTAG00000015991 and 282637, cadherin 1 |
| Identity | 1748 |
| Gene | CDH1 |
| Long gene name | cadherin 1 |
| Synonyms gene | UVO |
| Synonyms gene name | E-cadherin (epithelial) , cadherin 1, type 1 |
| Synonyms | uvomorulin CD324 |
| Synonyms name | E-Cadherin |
| Locus | 16q22, 1 |
| Discovery year | 1986-01-01 |
| GenBank acession | L08599 |
| Entrez gene record | 999 |
| Pubmed identfication | 9925936 |
| RefSeq identity | NM_004360 |
| Classification | Type I classical cadherins CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000137561 |
| Locus Specific Databases | LRG_301 |
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