Name : CDH12 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN1408604081
| Long name | CDH12 Primary Polyclonal Antibody |
| Also known as | CDH12 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CDH12 |
| Specificity | This is a highly specific antibody against CDH12 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CDH12 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | BR-cadherin (for brain-cadherin, Cadherins each contain a large extracellular domain at the amino terminus, The relatively short carboxy terminal, also designated cadherin-12 or N-cadherin 2) is expressed specifically in neurons in the central nervous system and is thought to be involved in neuronal development (8), including catenin b, intracellular domain interacts with a variety of cytoplasmic proteins, the most distal of which is thought to be responsible for binding specificity (5, to regulate cadherin function (7), which is characterized by a series of five homologous repeats, 6), The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morpho-genesis (1-4) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | BR-cadherin, Brain cadherin, CAD12_HUMAN, CDH12, CDHB, Cadherin 12, Cadherin 12 precursor, Cadherin 12 type 2, Cadherin 12 type 2 N cadherin 2, Cadherin neural type 2, Cadherin-12, FLJ34857, N cadherin 2, N-cadherin 2, Neural type cadherin 2, Neuronal cadherin 2, cadherin 12 N cadherin 2, Br cadherin |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CDH12 |
| Short name | CDH12 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | classification 2 (N-cadherin 2) (Antibody to), cadherin 12 |
| Alternative technique | antibodies |
| Alternative to gene target | BT, CDH12 and IDBG-13717 and ENSG00000154162 and 1010, CDHB, Cdh12 and IDBG-130694 and ENSMUSG00000040452 and 215654, Plasma membranes, calcium ion binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007156 and homophilic cell adhesion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0034329 and cell junction assembly and biological process this GO :0034332 and adherens junction organization and biological process this GO :0045216 and cell-cell junction organization and biological process, this GO :0005509: calcium ion binding, this GO :0005509: calcium ion binding, type 2 (N-cadherin 2), 41071 and IDBG-631013 and ENSBTAG00000025893 and 540672, cadherin 12 |
| Identity | 1751 |
| Gene | CDH12 |
| Long gene name | cadherin 12 |
| Synonyms gene name | cadherin 12, type 2 (N-cadherin 2) |
| Synonyms | Br-cadherin CDHB |
| Locus | 5p14, 3 |
| Discovery year | 1995-07-14 |
| GenBank acession | L33477 |
| Entrez gene record | 1010 |
| Pubmed identfication | 7731968 |
| RefSeq identity | NM_004061 |
| Classification | Type II classical cadherins |
| Havana BLAST/BLAT | OTTHUMG00000090591 |