Name : CDH12 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9988811037
| Long name | FITC Conjugated, CDH12 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CDH12 |
| Specificity | This is a highly specific antibody against CDH12 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human CDH12 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | BR-cadherin (for brain-cadherin, Cadherins each contain a large extracellular domain at the amino terminus, The relatively short carboxy terminal, also designated cadherin-12 or N-cadherin 2) is expressed specifically in neurons in the central nervous system and is thought to be involved in neuronal development (8), including catenin b, intracellular domain interacts with a variety of cytoplasmic proteins, the most distal of which is thought to be responsible for binding specificity (5, to regulate cadherin function (7), which is characterized by a series of five homologous repeats, 6), The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morpho-genesis (1-4) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | Br-cadherin CDHB |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CDH12 Conjugated |
| Short name | FITC Conjugated, CDH12 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | classification 2 (N-cadherin 2) (Antibody to), fluorecein coupled, cadherin 12 |
| Alternative technique | antibodies |
| Alternative to gene target | BT, CDH12 and IDBG-13717 and ENSG00000154162 and 1010, CDHB, Cdh12 and IDBG-130694 and ENSMUSG00000040452 and 215654, Plasma membranes, calcium ion binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007156 and homophilic cell adhesion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0034329 and cell junction assembly and biological process this GO :0034332 and adherens junction organization and biological process this GO :0045216 and cell-cell junction organization and biological process, this GO :0005509: calcium ion binding, this GO :0005509: calcium ion binding, type 2 (N-cadherin 2), 41071 and IDBG-631013 and ENSBTAG00000025893 and 540672, cadherin 12 |
| Identity | 1751 |
| Gene | CDH12 |
| Long gene name | cadherin 12 |
| Synonyms gene name | cadherin 12, type 2 (N-cadherin 2) |
| Locus | 5p14, 3 |
| Discovery year | 1995-07-14 |
| GenBank acession | L33477 |
| Entrez gene record | 1010 |
| Pubmed identfication | 7731968 |
| RefSeq identity | NM_004061 |
| Classification | Type II classical cadherins |
| Havana BLAST/BLAT | OTTHUMG00000090591 |