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CDH18 Antibody

CDH18 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCDH18 Primary Polyclonal Antibody
Also known asCDH18 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCDH18
SpecificityThis is a highly specific antibody against CDH18
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CDH18
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CDH14 (cadherin 14), CDH24 or CDH14L, EY-cadherin, EY-cadherin contains a highly conserved C-terminal domain characteristic of all cadherins, EY-cadherin functions as a type II classical cadherin that is expressed specifically in the central nervous system (CNS), EY-cadherin is thought to be involved in axon guidance and outgrowth, One of several members of the cadherin superfamily, Specifically, The gene encoding EY-cadherin is located within a region on chromosome five that is commonly deleted in carcinomas, also known as CDH18 (cadherin 18), as well as synaptic adhesion within the CNS, but lacks the HAV cell adhesion sequence that is specific to type I cadherins, implicating EY-cadherin as a potential tumor suppressor, is a 790 amino acid single-pass type I membrane protein that contains five cadherin domains, where it plays a role in cell-cell binding events, The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding events that are critical to the maintenance of cell structure and morphogenesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CDH14, CDH14L, CDH18, CDH24, Cadherin 14, Cadherin 18, Cadherin 18, Cadherin-14, Cadherin-18, Cadherin14, Cadherin18, EY CADHERIN, type 2, CAD18_HUMAN
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCDH18
Short nameCDH18 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name classification 2 (Antibody to), cadherin 18
Alternative techniqueantibodies
Alternative to gene target CDH14 and CDH14L and CDH24, CDH18 and IDBG-13642 and ENSG00000145526 and 1016, CDH18 and IDBG-631065 and ENSBTAG00000037844 and 512080, Cdh18 and IDBG-130778 and ENSMUSG00000040420 and 320865, Plasma membranes, calcium ion binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007156 and homophilic cell adhesion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0034329 and cell junction assembly and biological process this GO :0034332 and adherens junction organization and biological process this GO :0045216 and cell-cell junction organization and biological process, this GO :0005509: calcium ion binding, this GO :0005509: calcium ion binding, type 2, cadherin 18
Identity 1757
Gene CDH18
Long gene name cadherin 18
Synonyms gene name cadherin 18, type 2
Synonyms CDH14 EY-CADHERIN
Locus 5p14, 3
Discovery year 1997-06-25
GenBank acession U59325
Entrez gene record 1016
Pubmed identfication 9030594 10191097
RefSeq identity NM_004934
Classification Type II classical cadherins
Havana BLAST/BLAT OTTHUMG00000090578

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