Name : CDK14 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN8297135878
| Long name | FITC Conjugated, CDK14 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CDK14 |
| Specificity | This is a highly specific antibody against CDK14 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human CDK14/PFTK1 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3, May also play a role in meiosis, Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo, leading to the activation of the Wnt signaling pathway, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport, whose activity is controlled by an associated cyclin, Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | PFTAIRE1 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CDK14 Conjugated |
| Short name | FITC Conjugated, CDK14 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, CDK14 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 8883 |
| Gene | CDK14 |
| Long gene name | cyclin dependent kinase 14 |
| Synonyms gene | PFTK1 |
| Synonyms gene name | PFTAIRE protein kinase 1 |
| Locus | 7q21, 13 |
| Discovery year | 1996-07-26 |
| Entrez gene record | 5218 |
| Pubmed identfication | 9202329 11313143 19884882 |
| RefSeq identity | NM_012395 |
| Classification | Cyclin dependent kinases |
| Havana BLAST/BLAT | OTTHUMG00000023649 |