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cdk4 (AF10A4) Monoclonal Antibody

cdk4 (AF10A4) Monoclonal Antibody size: 0.1ml 362

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 362
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namecdk4 (AF10A4) Monoclonal Antibody
Also known ascdk4 (AF10A4) Monoclonal Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target Antigencdk4
SpecificityThis is a highly specific antibody against cdk4
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone numberAF10A4
Source)), Recombinant human protein purified from E, a, coli (MBP-CDK4 1-303 a
Gene ID number1019
Swiss ProtP11802
Tested ApplicationsWB
Recommended dilutions000), WB (1:2
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity, Component of the ternary complex, Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals, Hypophosphorylates RB1 in early G(1) phase, Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex, Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition
Purification methodAmmonium sulfate precipitation
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CDK4, Cell division protein kinase 4, Cyclin-dependent kinase 4, PSK-J3, CMM3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene targetcdk4 (AF10A4) Monoclonal
Short namecdk4 (AF10A4) Monoclonal Antibody
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative namecyclin-dependent kinase 4 (AF10A4) monoclonal (Antibody to)
Alternative techniqueantibodies

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