| Long name | CDK5 (8A1) Monoclonal Antibody |
| Also known as | CDK5 (8A1) Monoclonal Antibody |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CDK5 |
| Specificity | This is a highly specific antibody against CDK5 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 8A1 |
| Source | His-tagged recombinant human CDK5 protein purified from Baculovirus expressed insect cells |
| Gene ID number | 1020 |
| Swiss Prot | Q00535 |
| Tested Applications | IP, WB |
| Recommended dilutions | WB (1:1000 ~ 2000) IP (2 ul) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | And Its activity is detected almost exclusively in brain extracts, Cdk5 activity requires association with one of two brain-specific regulatory subunits called p35 and p39, Instead, Its mRNA and protein are expressed in kidney, Similar to other Cdks, The two activators regulate the spatial and temporal expression of active Cdk5 to restrict its activity primarily to post-mitotic neurons, and ovary, but Cdk5 is not activated by cyclins, monomeric Cdk5 displays no enzymatic activity, testes, Cyclin-dependent kinase-5 (CDK5) is a member of the cyclin-dependent kinase family of serine/threonine kinases |
| Purification method | Ammonium sulfate precipitation |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CDK5, CDKN5, Cell division protein kinase 5, Cyclin-dependent-like kinase 5, PSSALRE, Serine/threonine-protein kinase PSSALRE, TPKII catalytic subunit, Tau protein kinase II catalytic subunit, LIS7 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | CDK5 (8A1) Monoclonal |
| Short name | CDK5 (8A1) Monoclonal Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | cyclin-dependent kinase 5 (8A1) monoclonal (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CDK5 and IDBG-48977 and ENSG00000164885 and 1020, CDK5 and IDBG-637527 and ENSBTAG00000007766 and 281066, Cdk5 and IDBG-141112 and ENSMUSG00000028969 and 12568, DNA-templated and biological process this GO :0045956 and positive regulation of calcium ion-dependent exocytosis and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046826 and negative regulation of protein export from nucleus and biological process this GO :0046875 and ephrin receptor binding and molecular function this GO :0048148 and behavioral response to cocaine and biological process this GO :0048167 and regulation of synaptic plasticity and biological process this GO :0048488 and synaptic vesicle endocytosis and biological process this GO :0048511 and rhythmic process and biological process this GO :0048675 and axon extension and biological process this GO :0048709 and oli this GO dendrocyte differentiation and biological process this GO :0048812 and neuron projection morphogenesis and biological process this GO :0048813 and dendrite morphogenesis and biological process this GO :0050321 and tau-protein kinase activity and molecular function this GO :0051301 and cell division and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0060078 and regulation of postsynaptic membrane potential and biological process this GO :0060079 and regulation of excitatory postsynaptic membrane potential and biological process this GO :0061001 and regulation of dendritic spine morphogenesis and biological process this GO :0070509 and calcium ion import and biological process this GO :0071156 and regulation of cell cycle arrest and biological process this GO :0090314 and positive regulation of protein targeting to membrane and biological process this GO :1901215 and negative regulation of neuron death and biological process this GO :2000251 and positive regulation of actin cytoskeleton reorganization and biological process this GO :2000273 and positive regulation of receptor activity and biological process, PSSALRE, dopaminergic and biological process this GO :0002039 and p53 binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004693 and cyclin-dependent protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005176 and ErbB-2 class receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0006887 and exocytosis and biological process this GO :0006913 and nucleocytoplasmic transport and biological process this GO :0006915 and apoptotic process and biological process this GO :0007049 and cell cycle and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007409 and axonogenesis and biological process this GO :0007411 and axon guidance and biological process this GO :0007416 and synapse assembly and biological process this GO :0007519 and skeletal muscle tissue development and biological process this GO :0007596 and blood coagulation and biological process this GO :0008045 and motor neuron axon guidance and biological process this GO :0008092 and cytoskeletal protein binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008306 and associative learning and biological process this GO :0008542 and visual learning and biological process this GO :0009611 and response to wounding and biological process this GO :0009790 and embryo development and biological process this GO :0014044 and Schwann cell development and biological process this GO :0014069 and postsynaptic density and cellular component this GO :0016020 and membrane and cellular component this GO :0016079 and synaptic vesicle exocytosis and biological process this GO :0016301 and kinase activity and molecular function this GO :0016310 and phosphorylation and biological process this GO :0016477 and cell migration and biological process this GO :0016533 and cyclin-dependent protein kinase 5 holoenzyme complex and cellular component this GO :0016772 and transferase activity, glutamatergic and biological process this GO :0035418 and protein localization to synapse and biological process this GO :0042220 and response to cocaine and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043113 and receptor clustering and biological process this GO :0043125 and ErbB-3 class receptor binding and molecular function this GO :0043204 and perikaryon and cellular component this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0045055 and regulated secretory pathway and biological process this GO :0045211 and postsynaptic membrane and cellular component this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0045861 and negative regulation of proteolysis and biological process this GO :0045892 and negative regulation of transcription, nuclei, this GO :0001764 and neuron migration and biological process this GO :0001963 and synaptic transmission, this GO :0002039: p53 binding, this GO :0002039: p53 binding and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004693: cyclin-dependent protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005176: ErbB-2 class receptor binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008092: cytoskeletal protein binding and also this GO :0016301: kinase activity and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004693: cyclin-dependent protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005176: ErbB-2 class receptor binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008092: cytoskeletal protein binding, this GO :0016301: kinase activity, this GO :0016772: transferase activity, this GO :0030549: acetylcholine receptor activator activity, this GO :0043125: ErbB-3 class receptor binding, this GO :0046875: ephrin receptor binding, this GO :0050321: tau-protein kinase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0030549: acetylcholine receptor activator activity and also this GO :0043125: ErbB-3 class receptor binding and also this GO :0046875: ephrin receptor binding and also this GO :0050321: tau-protein kinase activity, transferring phosphorus-containing groups and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0018107 and peptidyl-threonine phosphorylation and biological process this GO :0019233 and sensory perception of pain and biological process this GO :0021537 and telencephalon development and biological process this GO :0021549 and cerebellum development and biological process this GO :0021695 and cerebellar cortex development and biological process this GO :0021697 and cerebellar cortex formation and biological process this GO :0021766 and hippocampus development and biological process this GO :0021819 and layer formation in cerebral cortex and biological process this GO :0021954 and central nervous system neuron development and biological process this GO :0021987 and cerebral cortex development and biological process this GO :0022038 and corpus callosum development and biological process this GO :0030027 and lamellipodium and cellular component this GO :0030054 and cell junction and cellular component this GO :0030175 and filopodium and cellular component this GO :0030182 and neuron differentiation and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0030426 and growth cone and cellular component this GO :0030517 and negative regulation of axon extension and biological process this GO :0030549 and acetylcholine receptor activator activity and molecular function this GO :0030866 and cortical actin cytoskeleton organization and biological process this GO :0030900 and forebrain development and biological process this GO :0031175 and neuron projection development and biological process this GO :0031397 and negative regulation of protein ubiquitination and biological process this GO :0031594 and neuromuscular junction and cellular component this GO :0031914 and negative regulation of synaptic plasticity and biological process this GO :0032092 and positive regulation of protein binding and biological process this GO :0032801 and receptor catabolic process and biological process this GO :0033136 and serine phosphorylation of STAT3 protein and biological process this GO :0035249 and synaptic transmission, cyclin-dependent kinase 5 |
| Identity | 1774 |
| Gene | CDK5 |
| Long gene name | cyclin dependent kinase 5 |
| Synonyms | PSSALRE |
| Locus | 7q36, 1 |
| Discovery year | 1993-07-28 |
| GenBank acession | X66364 |
| Entrez gene record | 1020 |
| Pubmed identfication | 8275715 1639063 |
| Classification | Cyclin dependent kinases |
| Havana BLAST/BLAT | OTTHUMG00000158414 |
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