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CDK5RAP2 Antibody

CDK5RAP2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCDK5RAP2 Primary Polyclonal Antibody
Also known asCDK5RAP2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCDK5RAP2
SpecificityThis is a highly specific antibody against CDK5RAP2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CDK5RAP2
Gene ID number55755
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CDK5RAP1 (CDK5 regulatory subunit-associated protein 1) specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity, CDK5RAP2, CDK5RAP2 associates with centrosomes throughout the cell cycle, Expressed in placenta, Mutations in the gene encoding CDK5RAP2 results in primary microencephaly autosomal recessive type 3, There are four isoforms of CDK5RAP2 that are produced as a result of alternative splicing events, also known as Centrosome-associated protein 215, brain and kidney, brain weight and significant neurological deficits, heart, is a 1893 amino acid centrosomal protein that regulates activity of CDK5 through complex formation with CDK5RAP1, liver, lung, pancreas, skeletal muscle, which is characterized by markedly reduced head size, Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CDK5 activator-binding protein C48, CDK5 regulatory subunit associated protein 2, CDK5 regulatory subunit-associated protein 2, CEP215, CK5P2_HUMAN, Centrosome-associated protein 215, MCPH3, centrosomal protein 215 kDa, C48
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCDK5RAP2
Short nameCDK5RAP2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCDK5RAP2 (Antibody to)
Alternative techniqueantibodies
Identity 18672
Gene CDK5RAP2
Long gene name CDK5 regulatory subunit associated protein 2
Synonyms gene MCPH3
Synonyms gene name microcephaly, primary autosomal recessive 3
Synonyms C48 FLJ10867 CEP215
Synonyms name centrosomin
Locus 9q33, 2
Discovery year 2002-07-22
GenBank acession BK005504
Entrez gene record 55755
Pubmed identfication 10721722 17764569 24466316
RefSeq identity NM_018249
Havana BLAST/BLAT OTTHUMG00000021043

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