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CDK5RAP2 Antibody, FITC Conjugated

CDK5RAP2 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, CDK5RAP2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCDK5RAP2
SpecificityThis is a highly specific antibody against CDK5RAP2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CDK5RAP2
Gene ID number55755
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CDK5RAP1 (CDK5 regulatory subunit-associated protein 1) specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity, CDK5RAP2, CDK5RAP2 associates with centrosomes throughout the cell cycle, Expressed in placenta, Mutations in the gene encoding CDK5RAP2 results in primary microencephaly autosomal recessive type 3, There are four isoforms of CDK5RAP2 that are produced as a result of alternative splicing events, also known as Centrosome-associated protein 215, brain and kidney, brain weight and significant neurological deficits, heart, is a 1893 amino acid centrosomal protein that regulates activity of CDK5 through complex formation with CDK5RAP1, liver, lung, pancreas, skeletal muscle, which is characterized by markedly reduced head size, Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms C48 FLJ10867 CEP215
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCDK5RAP2 Conjugated
Short name FITC Conjugated, CDK5RAP2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, CDK5RAP2 (Antibody to)
Alternative techniqueantibodies
Identity 18672
Gene CDK5RAP2
Long gene name CDK5 regulatory subunit associated protein 2
Synonyms gene MCPH3
Synonyms gene name microcephaly, primary autosomal recessive 3
Synonyms name centrosomin
Locus 9q33, 2
Discovery year 2002-07-22
GenBank acession BK005504
Entrez gene record 55755
Pubmed identfication 10721722 17764569 24466316
RefSeq identity NM_018249
Havana BLAST/BLAT OTTHUMG00000021043

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