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CDK6 (75B9) Monoclonal Antibody

CDK6 (75B9) Monoclonal Antibody size: 0.1ml 362

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 362
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCDK6 (75B9) Monoclonal Antibody
Also known asCDK6 (75B9) Monoclonal Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCDK6
SpecificityThis is a highly specific antibody against CDK6
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number75B9
SourceRecombinant human protein purified from E, coli
Gene ID number1021
Swiss ProtQ00534
Tested ApplicationsWB
Recommended dilutionsWB (1:500)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Delays senescence, Essential for cell proliferation within the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricles, Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle, Involved in initiation and maintenance of cell cycle exit during cell differentiation, May play a role in the centrosome organization during the cell cycle phases (PubMed:23918663), Phosphorylates pRB/RB1 and NPM1, Prevents myeloid differentiation by interfering with RUNX1 and reducing its transcription transactivation activity, Promotes, Promotes the production of newborn neurons, Promotes the proliferation of beta-cells in pancreatic islets of Langerhans, Required during thymocyte development, and enhanced motility during cell differentiation, at least in astrocytes, but is required for the proliferation of specific cell types (e, but promotes proliferation of normal myeloid progenitors, changes in patterns of gene expression, changes in the actin cytoskeleton including loss of stress fibers, erythroid and hematopoietic cells), prevents cell proliferation and regulates negatively cell differentiation, probably by modulating G1 length, promotes G1/S transition, Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation, g
Purification methodAmmonium sulfate precipitation
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CDK6, CDKN6, Cell division protein kinase 6, Cyclin-dependent kinase 6, PLSTIRE, Serine/threonine-protein kinase PLSTIRE, MCPH12
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene targetCDK6 (75B9) Monoclonal
Short nameCDK6 (75B9) Monoclonal Antibody
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative nameCDK6 (75B9) monoclonal (Antibody to)
Alternative techniqueantibodies
Identity 1777
Gene CDK6
Long gene name cyclin dependent kinase 6
Synonyms PLSTIRE
Locus 7q21, 2
Discovery year 1994-02-14
Entrez gene record 1021
Pubmed identfication 1639063
Classification Cyclin dependent kinases
Havana BLAST/BLAT OTTHUMG00000131697
Locus Specific Databases LRG_991

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