| Long name | ALEXA FLUOR 488 Conjugated, CDKN1B Polyclonal Antibody |
| Also known as | Anti-CDKN1B PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CDKN1B |
| Specificity | This is a highly specific antibody against CDKN1B |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 150-198/198 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CDKN1B |
| Gene ID Number | 1027 |
| Swiss Prot | P46527 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry, Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, Involved in G1 arrest, Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes, and modulation of CCND1-CDK4 complex activation, stability, Important regulator of cell cycle progression |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | KIP1 P27KIP1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CDKN1B Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | CDKN1B |
| Short name | CDKN1B Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Kip1) (Antibody to), cyclin-dependent kinase inhibitor 1B (p27 |
| Alternative technique | antibodies |
| Alternative to gene target | CDKN1B and IDBG-20317 and ENSG00000111276 and 1027, CDKN1B and IDBG-639416 and ENSBTAG00000018254 and 512613, CDKN4 and KIP1 and MEN1B and MEN4 and P27KIP1, Cdkn1b and IDBG-194318 and ENSMUSG00000003031 and 12576, DNA-templated and biological process this GO :0045930 and negative regulation of mitotic cell cycle and biological process this GO :0046686 and response to cadmium ion and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048102 and autophagic cell death and biological process this GO :0048839 and inner ear development and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0051087 and chaperone binding and molecular function this GO :0051271 and negative regulation of cellular component movement and biological process this GO :0060770 and negative regulation of epithelial cell proliferation involved in prostate gland development and biological process this GO :0071236 and cellular response to antibiotic and biological process this GO :0071285 and cellular response to lithium ion and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071850 and mitotic cell cycle arrest and biological process this GO :0071901 and negative regulation of protein serine/threonine kinase activity and biological process, Kip1), cytoplasmic mediator activity, cytoplasmic mediator activity and also this GO :0005515: protein binding and also this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process and also this GO :0019903: protein phosphatase binding and also this GO :0030544: Hsp70 protein binding and also this GO :0032403: protein complex binding and also this GO :0051087: chaperone binding, cytoplasmic mediator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0006813 and potassium ion transport and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006977 and DNA damage response, nuclei, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0008219 and cell death and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0009749 and response to glucose and biological process this GO :0010942 and positive regulation of cell death and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0019903 and protein phosphatase binding and molecular function this GO :0030308 and negative regulation of cell growth and biological process this GO :0030544 and Hsp70 protein binding and molecular function this GO :0031116 and positive regulation of microtubule polymerization and biological process this GO :0032355 and response to estradiol and biological process this GO :0032403 and protein complex binding and molecular function this GO :0033673 and negative regulation of kinase activity and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042326 and negative regulation of phosphorylation and biological process this GO :0042493 and response to drug and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043200 and response to amino acid and biological process this GO :0043234 and protein complex and cellular component this GO :0043434 and response to peptide hormone and biological process this GO :0045087 and innate immune response and biological process this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0045736 and negative regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0045892 and negative regulation of transcription, this GO :0000079 and regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0001666 and response to hypoxia and biological process this GO :0004861 and cyclin-dependent protein serine/threonine kinase inhibitor activity and molecular function this GO :0005072 and transforming growth factor beta receptor, this GO :0004861: cyclin-dependent protein serine/threonine kinase inhibitor activity, this GO :0004861: cyclin-dependent protein serine/threonine kinase inhibitor activity and also this GO :0005072: transforming growth factor beta receptor, this GO :0005072: transforming growth factor beta receptor, this GO :0005515: protein binding, this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0019903: protein phosphatase binding, this GO :0030544: Hsp70 protein binding, this GO :0032403: protein complex binding, this GO :0051087: chaperone binding, transforming growth factor beta receptor, cyclin-dependent kinase inhibitor 1B (p27 |
| Identity | 1785 |
| Gene | CDKN1B |
| Long gene name | cyclin dependent kinase inhibitor 1B |
| Synonyms gene name | Kip1) , cyclin-dependent kinase inhibitor 1B (p27 |
| Locus | 12p13, 1 |
| Discovery year | 1995-09-14 |
| GenBank acession | AF480891 |
| Entrez gene record | 1027 |
| Pubmed identfication | 8033212 |
| RefSeq identity | NM_004064 |
| Havana BLAST/BLAT | OTTHUMG00000149914 |
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