| Long name | ALEXA FLUOR 350 Conjugated, CDKN2A/p19ARF Polyclonal Antibody |
| Also known as | Anti-CDKN2A/p19ARF PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CDKN2A/p19ARF |
| Specificity | This is a highly specific antibody against CDKN2A/p19ARF |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 70-100/169 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from mouse CDKN2A/p19ARF |
| Gene ID Number | 12578 |
| Swiss Prot | P51480 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Rat, Mouse |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein, Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6 |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | CDK4I p16 INK4a MTS1 CMM2 ARF p19 p14 INK4 p16INK4a p19Arf p14ARF |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | CDKN2A/p19ARF |
| Short name | CDKN2A/p19ARF Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, cyclin-dependent kinase inhibitor 2A/p19ARF (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | ARF and CDK4I and CDKN2 and CMM2 and INK4 and INK4A and MLM and MTS-1 and MTS1 and P14 and P14ARF and P16 and P16-INK4A and P16INK4 and P16INK4A and P19 and P19ARF and TP16, CDKN2A and IDBG-54547 and ENSG00000147889 and 1029, CDKN2A and IDBG-630043 and ENSBTAG00000034220 and 616369, DNA-templated and biological process this GO :0006364 and rRNA processing and biological process this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008637 and apoptotic mitochondrial changes and biological process this GO :0010389 and regulation of G2/M transition of mitotic cell cycle and biological process this GO :0016301 and kinase activity and molecular function this GO :0016310 and phosphorylation and biological process this GO :0016604 and nuclear body and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0030308 and negative regulation of cell growth and biological process this GO :0030889 and negative regulation of B cell proliferation and biological process this GO :0031647 and regulation of protein stability and biological process this GO :0031648 and protein destabilization and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0033088 and negative regulation of immature T cell proliferation in thymus and biological process this GO :0033235 and positive regulation of protein sumoylation and biological process this GO :0034393 and positive regulation of smooth muscle cell apoptotic process and biological process this GO :0035985 and senescence-associated heterochromatin focus and cellular component this GO :0035986 and senescence-associated heterochromatin focus assembly and biological process this GO :0042326 and negative regulation of phosphorylation and biological process this GO :0043234 and protein complex and cellular component this GO :0043517 and positive regulation of DNA damage response, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046825 and regulation of protein export from nucleus and biological process this GO :0048103 and somatic stem cell division and biological process this GO :0050821 and protein stabilization and biological process this GO :0051059 and NF-kappaB binding and molecular function this GO :0051444 and negative regulation of ubiquitin-protein transferase activity and biological process this GO :0055105 and ubiquitin-protein transferase inhibitor activity and molecular function this GO :0070534 and protein K63-linked ubiquitination and biological process this GO :0071158 and positive regulation of cell cycle arrest and biological process this GO :0090398 and cellular senescence and biological process this GO :0090399 and replicative senescence and biological process this GO :0097371 and MDM2/MDM4 family protein binding and molecular function this GO :1902510 and regulation of apoptotic DNA fragmentation and biological process this GO :2000111 and positive regulation of macrophage apoptotic process and biological process this GO :2000774 and positive regulation of cellular senescence and biological process, MDM2/MDM4 family protein binding, nuclei, signal transduction by p53 class mediator and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045736 and negative regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0045892 and negative regulation of transcription, this GO :0000075 and cell cycle checkpoint and biological process this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000209 and protein polyubiquitination and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0001953 and negative regulation of cell-matrix adhesion and biological process this GO :0002039 and p53 binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0004861 and cyclin-dependent protein serine/threonine kinase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0002039: p53 binding, this GO :0002039: p53 binding and also this GO :0003677: DNA binding and also this GO :0004861: cyclin-dependent protein serine/threonine kinase inhibitor activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0016301: kinase activity and also this GO :0019901: protein kinase binding and also this GO :0044822: poly(A) RNA binding and also this GO :0051059: NF-kappaB binding and also this GO :0055105: ubiquitin-protein transferase inhibitor activity and also this GO :0097371: MDM2/MDM4 family protein binding, this GO :0003677: DNA binding, this GO :0004861: cyclin-dependent protein serine/threonine kinase inhibitor activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0016301: kinase activity, this GO :0019901: protein kinase binding, this GO :0044822: poly(A) RNA binding, this GO :0051059: NF-kappaB binding, this GO :0055105: ubiquitin-protein transferase inhibitor activity, this GO :0097371: MDM2/MDM4 family protein binding, cyclin-dependent kinase inhibitor 2A |
| Identity | 1787 |
| Gene | CDKN2A |
| Long gene name | cyclin dependent kinase inhibitor 2A |
| Synonyms gene | CDKN2 MLM |
| Synonyms gene name | cyclin-dependent kinase inhibitor 2A (melanoma, inhibits CDK4) , p16 |
| Locus | 9p21, 3 |
| Discovery year | 1994-05-19 |
| GenBank acession | L27211 |
| Entrez gene record | 1029 |
| Pubmed identfication | 8152487 7606716 |
| RefSeq identity | NM_000077 |
| Havana BLAST/BLAT | OTTHUMG00000019686 |
| Locus Specific Databases | LOVD - Leiden Open Variation Database LRG_11 |
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