Name : CDX1 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN5847205506
| Long name | FITC Conjugated, CDX1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CDX1 |
| Specificity | This is a highly specific antibody against CDX1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human CDX1 |
| Gene ID number | 1044 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | A decrease in human Cdx1 and/or Cdx2 expression is associated with colorectal tumorigenesis, Both Cdx1 and Cdx2 genes must be expressed to reduce tumorigenic potential, Cdx1 and Cdx2 are expressed in the small intestine and colon of fetus and adult, Cdx1 positively regulates its own expression, Cdx2, Expression of the Cdx1 homeobox gene in epithelial intestinal cells promotes cellular growth and differentiation, The human Cdx1 gene maps to chromosome 5q31-q33 and encodes a 265-amino acid protein, The intestine-specific transcription factors Cdx1 and Cdx2 are candidate genes for directing intestinal development, The relative expression of Cdx1 to Cdx2 protein may be important in the anterior to posterior patterning of the intestinal epithelium and in defining patterns of proliferation and differentiation along the crypt-villus axis, and Cdx4) are members of the caudal-type homeobox family of genes, differentiation, gene required for anterior-posterior regional identity, proliferation and maintenance of the intestinal phenotype, suggesting that the two genes control the normal phenotype by independent pathways, to increase sensitivity to apoptosis and to reduce cell migration, which are homologues of the Drosophila â, &euro, &euro, &tilde, &trade, The members of the murine Cdx family (Cdx1, caudalâ |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CDX1 Conjugated |
| Short name | FITC Conjugated, CDX1 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, CDX1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1805 |
| Gene | CDX1 |
| Long gene name | caudal type homeobox 1 |
| Synonyms gene name | caudal type homeo box transcription factor 1 |
| Locus | 5q32 |
| Discovery year | 1995-05-05 |
| GenBank acession | U51095 |
| Entrez gene record | 1044 |
| Pubmed identfication | 8530027 |
| RefSeq identity | NM_001804 |
| Classification | HOXL subclass homeoboxes |
| Havana BLAST/BLAT | OTTHUMG00000169772 |