Name : CEA (3G7) Monoclonal Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN1374571616
| Long name | ALEXA FLUOR 488 Conjugated, CEA (3G7) Monoclonal Antibody |
| Also known as | Anti-CEA MAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Mouse (Mus musculus) |
| Target Antigen | CEA |
| Specificity | This is a highly specific antibody against CEA |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Monoclonal |
| Clone | 3G7 |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CEA/CEACAM5 |
| Gene ID Number | 1048 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members, CEACAM molecules are differentially expressed in epithelial cells or in leucocytes, CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor, It consists of seven CEACAM (CEACAM 1, Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker, The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains, The function of CEACAM family members varies widely: they function as cell adhesion molecules, receptors of Neisseria species and other bacteria, regulators of lymphocyte and dendritic cell activation, tumor suppressors, CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family |
| Purification | Purified by Protein G |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | CD66e |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CEA (3G7) Monoclonal Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | CEA (3G7) Monoclonal |
| Short name | CEA (3G7) Monoclonal Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, CEA (3G7) monoclonal (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1817 |
| Gene | CEACAM5 |
| Long gene name | carcinoembryonic antigen related cell adhesion molecule 5 |
| Synonyms gene | CEA |
| Synonyms gene name | carcinoembryonic antigen-related cell adhesion molecule 5 |
| Locus | 19q13, 2 |
| Discovery year | 1986-01-01 |
| GenBank acession | M17303 |
| Entrez gene record | 1048 |
| RefSeq identity | NM_004363 |
| Classification | I-set domain containing Immunoglobulin like domain containing CD molecules V-set domain containing Carcinoembryonic antigen related cell adhesion molecule family |
| Havana BLAST/BLAT | OTTHUMG00000151061 |