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CECR1 Antibody

CECR1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCECR1 Primary Polyclonal Antibody
Also known asCECR1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCECR1
SpecificityThis is a highly specific antibody against CECR1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CECR1/ADGF
Gene ID number51816
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified, Adenosine deaminase degrades extracellular adenosine, CECR family members are widely expressed, CECR1 has the highest expression in adult heart, CECR2, CECR2 is also involved in neurulation and chromatin remodeling, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9, CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, It is a candidate gene for cat eye syndrome, It may act as a growth factor and have adenosine deaminase activity, Mutations in the CECR2 gene result in neural tube defects, Specifically, The cat eye syndrome critical region protein (CECR) family includes CECR1, The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES), Two transcript variants encoding distinct isoforms have been identified for this gene, a developmental disorder associated with the duplication of a 2 Mb region of 22q11, although in some tissues it is associated with adenosine deaminase-binding protein, and normal or near-normal mental development, downslanting palpebral fissures, frequent occurrence of heart and renal malformations, lung, lymphoblasts and placenta, preauricular tags and/or pits, which is toxic for lymphocytes, 2, Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, CECR1 is a member of the adenosine and AMP deaminases family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CECR 1, CECR1_HUMAN, Cat eye syndrome chromosome region candidate 1, Cat eye syndrome critical region protein 1, Cat eye syndrome critical region protein 1 precursor, IDGFL, ADGF
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCECR1
Short nameCECR1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name candidate 1 (Antibody to), catalase eye syndrome chromosome region
Alternative techniqueantibodies
Alternative to gene target CECR1 and IDBG-641275 and ENSBTAG00000017313 and 617805, CECR1 and IDBG-933 and ENSG00000093072 and 51816, Extracellular, candidate 1, proteoglycan binding, this GO :0004000 and adenosine deaminase activity and molecular function this GO :0005615 and extracellular space and cellular component this GO :0006154 and adenosine catabolic process and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008152 and metabolic process and biological process this GO :0008201 and heparin binding and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0019239 and deaminase activity and molecular function this GO :0031685 and adenosine receptor binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043103 and hypoxanthine salvage and biological process this GO :0043394 and proteoglycan binding and molecular function this GO :0046103 and inosine biosynthetic process and biological process, this GO :0004000: adenosine deaminase activity, this GO :0004000: adenosine deaminase activity and also this GO :0008083: growth factor activity and also this GO :0008201: heparin binding and also this GO :0008270: zinc ion binding and also this GO :0019239: deaminase activity and also this GO :0031685: adenosine receptor binding and also this GO :0042803: protein homodimerization activity and also this GO :0043394: proteoglycan binding, this GO :0008083: growth factor activity, this GO :0008201: heparin binding, this GO :0008270: zinc ion binding, this GO :0019239: deaminase activity, this GO :0031685: adenosine receptor binding, this GO :0042803: protein homodimerization activity, this GO :0043394: proteoglycan binding, cat eye syndrome chromosome region
Identity 1839
Gene ADA2
Long gene name adenosine deaminase 2
Synonyms gene IDGFL CECR1
Synonyms gene name candidate 1 , cat eye syndrome chromosome region
Synonyms ADGF
Locus 22q11, 1
Discovery year 1999-12-09
GenBank acession AF190746
Entrez gene record 51816
Pubmed identfication 10756095 27663683
Classification Adenosine deaminase family
Havana BLAST/BLAT OTTHUMG00000030726

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