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CENPB Antibody

CENPB Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCENPB Primary Polyclonal Antibody
Also known asCENPB PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCENPB
SpecificityThis is a highly specific antibody against CENPB
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CENPB
Gene ID number1059
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen (referenced from Entrez Gene), It is a DNA-binding protein containing a helix loop helix DNA binding motif at the N-terminus, It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere , The DNA binding domain recognizes and binds a 17 bp sequence (CENPB box) in the centromeric satellite DNA, This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes, and a dimerization domain at the C-terminus, This gene product is a highly conserved protein associated with the centromere
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CENP-B, CENPB_HUMAN, Centromere protein B, Major centromere autoantigen B, centromere autoantigen B, CENP B
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCENPB
Short nameCENPB Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCENPB (Antibody to)
Alternative techniqueantibodies
Identity 1852
Gene CENPB
Long gene name centromere protein B
Synonyms gene name 80kDa , centromere protein B (80kD) centromere protein B
Locus 20p13
Discovery year 1988-05-31
GenBank acession X05299
Entrez gene record 1059
Pubmed identfication 8406460 11884609
RefSeq identity NM_001810
Classification Helix-turn-helix CENPB type domain containing
Havana BLAST/BLAT OTTHUMG00000031761

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