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CHD5 Antibody / Chromodomain-helicase-DNA-binding protein 5

CHD5 Antibody / Chromodomain-helicase-DNA-binding protein 5 size: 0.05 ml 199

Supplier NJS POLY
Price 199
Size 0.05 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCHD5 / Chromodomain-helicase-DNA-binding protein 5
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutionsWestern blot: 1:1000-2000
Intented useThis CHD5 antibodyis to be used only for research purposes and not for diagnostics
Gene ID #26038
Uniprot #Q8TDI0
PurityAntigen affinity
Description Downstream activated genes may include CDKN2A that positively regulates the p53/TP53 pathway, In parallel, In spermatogenesis, May specifically recognize and bind trimethylated 'Lys-27' (H3K27me3) and non- methylated 'Lys-4' of histone H3, Plays a role in the development of the nervous system by activating the expression of genes promoting neuron terminal differentiation, Tumor suppressor, a crucial step in the condensation of spermatid chromatin and the production of functional spermatozoa, it may also positively regulate the trimethylation of histone H3 at 'Lys- 27' thereby specifically repressing genes that promote the differentiation into non-neuronal cell lineages, it probably regulates histone hyperacetylation and the replacement of histones by transition proteins in chromatin, it regulates the expression of genes involved in cell proliferation and differentiation, prevents cell proliferation, which in turn, Chromodomain-helicase-DNA-binding protein 5 is a chromatin-remodeling protein that binds DNA through histones and regulates gene transcription
ImmunogenA portion of amino acids 64-98 from the human protein was used as the immunogen for the CHD5 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CHD5 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCHD5 / Chromodomain-helicase-DNA-binding protein 5
Short nameCHD5 Antibody / Chromodomain-helicase-DNA-binding protein 5
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCHD5 (Antibody to) / Chromodomain-helicase-Desoxyribonucleic acid-binding protein 5
Alternative techniqueantibodies
Identity 16816
Gene CHD5
Long gene name chromodomain helicase DNA binding protein 5
Locus 1p36, 31
Discovery year 2002-11-29
GenBank acession AF425231
Entrez gene record 26038
Pubmed identfication 11889561 12592387
RefSeq identity NM_015557
Classification NuRD complex PHD finger proteins
Havana BLAST/BLAT OTTHUMG00000000952

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