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CHEK1 (Ser280) Antibody

CHEK1 (Ser280) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCHEK1 (Ser280) Primary Polyclonal Antibody
Also known asCHEK1 (Ser280) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCHEK1 Ser280
SpecificityThis is a highly specific antibody against CHEK1 Ser280
Modification(s)Phosphorylation
Modification site(s)Ser280
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from mouse CHEK1 around the phosphorylation site of Ser280
Gene ID number1111
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA, Oct 2011], Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks, Several alternatively spliced transcript variants have been found for this gene, This protein acts to integrate signals from ATM and ATR, [provided by RefSeq, that also associate with chromatin in meiotic prophase I, two cell cycle proteins involved in DNA damage responses, The protein encoded by this gene belongs to the Ser/Thr protein kinase family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 1, C85740, CHEK 1, CHEK-1, CHEK1, CHEK1 phospho Ser280, CHEK1 phospho Ser280, CHK1 checkpoint homolog S, CHK1_HUMAN, Cell cycle checkpoint kinase, Checkpoint, Checkpoint kinase 1, Checkpoint kinase 1 homolog S, Chk 1, Chk1, EC 2, S, STT3, Serine/threonine protein kinase Chk1, Serine/threonine-protein kinase CHK1, cerevisiae, homolog A S, homolog of, p-CHEK1 Ser280, pombe, pombe, pombe, rad27, subunit of the oligosaccharyltransferase complex, 1, 7, 11, Chk1 Ser280
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCHEK1 (Ser280)
Short nameCHEK1 (Ser280) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCHEK1 (Ser280) (Antibody to)
Alternative techniqueantibodies
Identity 1925
Gene CHEK1
Long gene name checkpoint kinase 1
Synonyms gene name CHK1 (checkpoint, S, pombe) , pombe) homolog CHK1 checkpoint homolog (S
Synonyms CHK1
Locus 11q24, 2
Discovery year 1998-04-21
GenBank acession AF016582 BC017575
Entrez gene record 1111
Pubmed identfication 9278511 9382850
RefSeq identity NM_001274
Havana BLAST/BLAT OTTHUMG00000165853

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