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CHEK1 (Ser296) Antibody, FITC Conjugated

CHEK1 (Ser296) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, CHEK1 (Ser296) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCHEK1 Ser296
SpecificityThis is a highly specific antibody against CHEK1 Ser296
ModificationPhosphorylation
Modification siteSer296
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human CHEK1 isoform b around the phosphorylation site of Ser296
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA, Oct 2011], Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks, Several alternatively spliced transcript variants have been found for this gene, This protein acts to integrate signals from ATM and ATR, [provided by RefSeq, that also associate with chromatin in meiotic prophase I, two cell cycle proteins involved in DNA damage responses, The protein encoded by this gene belongs to the Ser/Thr protein kinase family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms CHK1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCHEK1 (Ser296) Conjugated
Short name FITC Conjugated, CHEK1 (Ser296) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, CHEK1 (Ser296) (Antibody to)
Alternative techniqueantibodies
Identity 1925
Gene CHEK1
Long gene name checkpoint kinase 1
Synonyms gene name CHK1 (checkpoint, S, pombe) , pombe) homolog CHK1 checkpoint homolog (S
Locus 11q24, 2
Discovery year 1998-04-21
GenBank acession AF016582 BC017575
Entrez gene record 1111
Pubmed identfication 9278511 9382850
RefSeq identity NM_001274
Havana BLAST/BLAT OTTHUMG00000165853

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