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Chloride Channel 5 Antibody

Chloride Channel 5 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameChloride Channel 5 Primary Polyclonal Antibody
Also known asChloride Channel 5 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenChloride Channel 5
SpecificityThis is a highly specific antibody against Chloride Channel 5
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationMitochondrion
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Chloride Channel 5/CLC5
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 1p36 and 16p13, 3q28, 4q32, CLC1 is highly expressed in skeletal muscle, CLC2 is highly expressed in the epithelia of several organs including lung, CLC3 expression is particularly abundant in neuronal tissue, CLC6 and CLC7 are broadly expressed in several tissues including testis, CLCs regulate excitability in muscle and nerve cells, Mutations in the gene encoding CLC1 lead to myotonia, Mutations in the gene encoding CLC5 lead to Dentâ, The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, Xp11, Xp22, a critical component of all living cells, a renal disorder characterized by proteinuria and hypercalciuria, aid in organic solute transport and maintain cellular volume, an inheritable disorder characterized by muscle stiffness and renal salt wasting, brain and muscle, kidney, respectively, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain, &euro, &trade, 23-p11, 3, 22, The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, s disease
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CLC5, CLCK2, CLCN5, CLCN5_HUMAN, Chloride transporter ClC-5, ClC-5, DENTS, H+/Cl- exchange transporter 5, NPHL1, NPHL2, XLRH, XRN, hCIC-K2, Chloride channel protein 5
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetChloride Channel 5
Short nameChloride Channel 5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameChloride Channel 5 (Antibody to)
Alternative techniqueantibodies
Identity 13517
Gene CLIC5
Long gene name chloride intracellular channel 5
Synonyms DFNB102
Locus 6p21, 1
Discovery year 2000-10-31
GenBank acession AF216941
Entrez gene record 53405
Pubmed identfication 10793131 24781754
Classification Chloride intracellular channels Deafness associated genes
Havana BLAST/BLAT OTTHUMG00000014775

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