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Chloride Channel 5 Antibody, ALEXA FLUOR 488

Chloride Channel 5 Antibody, ALEXA FLUOR 488 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 488 Conjugated, Chloride Channel 5 Polyclonal Antibody
Also known asAnti-Chloride Channel 5 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenChloride Channel 5
SpecificityThis is a highly specific antibody against Chloride Channel 5
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationMitochondrion
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Chloride Channel 5/CLC5
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen 1p36 and 16p13, 3q28, 4q32, CLC1 is highly expressed in skeletal muscle, CLC2 is highly expressed in the epithelia of several organs including lung, CLC3 expression is particularly abundant in neuronal tissue, CLC6 and CLC7 are broadly expressed in several tissues including testis, CLCs regulate excitability in muscle and nerve cells, Mutations in the gene encoding CLC1 lead to myotonia, Mutations in the gene encoding CLC5 lead to Dentâ, The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, Xp11, Xp22, a critical component of all living cells, a renal disorder characterized by proteinuria and hypercalciuria, aid in organic solute transport and maintain cellular volume, an inheritable disorder characterized by muscle stiffness and renal salt wasting, brain and muscle, kidney, respectively, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain, &euro, &trade, 23-p11, 3, 22, The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, s disease
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms DFNB102
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Chloride Channel 5 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetChloride Channel 5
Short nameChloride Channel 5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Chloride Channel 5 (Antibody to)
Alternative techniqueantibodies
Identity 13517
Gene CLIC5
Long gene name chloride intracellular channel 5
Locus 6p21, 1
Discovery year 2000-10-31
GenBank acession AF216941
Entrez gene record 53405
Pubmed identfication 10793131 24781754
Classification Chloride intracellular channels Deafness associated genes
Havana BLAST/BLAT OTTHUMG00000014775

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