Name : Chloride Channel 5 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9945132789
| Long name | FITC Conjugated, Chloride Channel 5 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Chloride Channel 5 |
| Specificity | This is a highly specific antibody against Chloride Channel 5 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Mitochondrion |
| Source | KLH conjugated synthetic peptide derived from human Chloride Channel 5/CLC5 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | 1p36 and 16p13, 3q28, 4q32, CLC1 is highly expressed in skeletal muscle, CLC2 is highly expressed in the epithelia of several organs including lung, CLC3 expression is particularly abundant in neuronal tissue, CLC6 and CLC7 are broadly expressed in several tissues including testis, CLCs regulate excitability in muscle and nerve cells, Mutations in the gene encoding CLC1 lead to myotonia, Mutations in the gene encoding CLC5 lead to Dentâ, The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, Xp11, Xp22, a critical component of all living cells, a renal disorder characterized by proteinuria and hypercalciuria, aid in organic solute transport and maintain cellular volume, an inheritable disorder characterized by muscle stiffness and renal salt wasting, brain and muscle, kidney, respectively, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain, &euro, &trade, 23-p11, 3, 22, The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, s disease |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | CLC5, CLCK2, CLCN5, CLCN5_HUMAN, Chloride transporter ClC-5, ClC-5, DENTS, H+/Cl- exchange transporter 5, NPHL1, NPHL2, XLRH, XRN, hCIC-K2, Chloride channel protein 5 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Chloride Channel 5 Conjugated |
| Short name | FITC Conjugated, Chloride Channel 5 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, Chloride Channel 5 (Antibody to) |
| Alternative technique | antibodies |