CHMP1A Antibody

CHMP1A Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 263

Size 0.1ml

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Long name	CHMP1A Primary Polyclonal Antibody
Also known as	CHMP1A PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	CHMP1A
Specificity	This is a highly specific antibody against CHMP1A
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen range	70-120/196
Subcellular location	Cell membrane, Nucleus, Cytoplasm
Source	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CHMP1A
Gene ID number	5119
Swiss Prot	Q9HD42
Tested Applications	IF(IHC-P), IHC-P, WB
Recommended dilutions	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	-I, ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released, Involved in cytokinesis, Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells, MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, May also be involved in chromosome condensation, May play a role in stable cell cycle progression and in PcG gene silencing, Targets the Polycomb group (PcG) protein BMI1/PCGF4 to regions of condensed chromatin, The ESCRT machinery also functions in topologically equivalent membrane fission events, The MVB pathway appears to require the sequential function of ESCRT-O, lysosomal enzymes and lipids, possibly in conjunction with the AAA ATPase VPS4, such as stimulated growth factor receptors, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses), -II and -III complexes, Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	CHMP1, CHMP1a, Charged multivesicular body protein 1a, Chromatin-modifying protein 1a, KIAA0047, PCOLN3, PRSM1, VPS46-1, VPS46A, Vacuolar protein sorting-associated protein 46-1, hVps46-1, PCH8
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	CHMP1A
Short name	CHMP1A Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	CHMP1A (Antibody to)
Alternative technique	antibodies
Identity	8740
Gene	CHMP1A
Long gene name	charged multivesicular body protein 1A
Synonyms gene	PRSM1 PCOLN3
Synonyms gene name	procollagen (type III) N-endopeptidase chromatin modifying protein 1A
Synonyms	KIAA0047 CHMP1 Vps46A
Locus	16q24, 3
Discovery year	1993-05-03
GenBank acession	U58048
Entrez gene record	5119
Pubmed identfication	11559748 11559747
RefSeq identity	NM_002768
Classification	Charged multivesicular body proteins ESCRT-III associated factors
Havana BLAST/BLAT	OTTHUMG00000169521

CHMP1A Antibody

CHMP1A Antibody size: 0.1ml 263

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