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CHMP2A Antibody

CHMP2A Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCHMP2A Primary Polyclonal Antibody
Also known asCHMP2A PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCHMP2A
SpecificityThis is a highly specific antibody against CHMP2A
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range20-50/222
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CHMP2A
Gene ID number27243
Swiss ProtO43633
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen -I, ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released, Involved in HIV-1 p6- and p9-dependent virus release, MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, The ESCRT machinery also functions in topologically equivalent membrane fission events, The MVB pathway appears to require the sequential function of ESCRT-O, lysosomal enzymes and lipids, possibly in conjunction with the AAA ATPase VPS4, such as stimulated growth factor receptors, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses), -II and -III complexes, Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BC-2, CHMP2, CHMP2a, Charged multivesicular body protein 2a, Chromatin-modifying protein 2a, Putative breast adenocarcinoma marker BC-2, VPS2, VPS2A, Vacuolar protein sorting-associated protein 2-1, Vps2-1, hVps2-1, BC2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCHMP2A
Short nameCHMP2A Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCHMP2A (Antibody to)
Alternative techniqueantibodies
Identity 30216
Gene CHMP2A
Long gene name charged multivesicular body protein 2A
Synonyms gene name chromatin modifying protein 2A
Synonyms BC-2 CHMP2 VPS2 VPS2A
Synonyms name cerevisiae) , putative breast adenocarcinoma marker (32kD) VPS2 homolog A (S
Locus 19q13, 43
Discovery year 2005-04-04
GenBank acession AF042384
Entrez gene record 27243
Pubmed identfication 15173323 11559748
RefSeq identity NM_014453
Classification Charged multivesicular body proteins ESCRT-III
Havana BLAST/BLAT OTTHUMG00000183547

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