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Chondroitin sulfate proteoglycan NG2 Antibody

Chondroitin sulfate proteoglycan NG2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameChondroitin sulfate proteoglycan NG2 Antibody
Also known asChondroitin sulfate proteoglycan NG2 Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenChondroitin sulfate proteoglycan NG2
SpecificityThis is a highly specific antibody against Chondroitin sulfate proteoglycan NG2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range730-780/2322
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Chondroitin sulfate proteoglycan NG2
Gene ID number1464
Swiss ProtQ6UVK1
Tested Applications IF(IHC-P), IHC-P, FCM
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), FCM(1:20-100)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ACK1 and BCAR1, Binds through its extracellular N-terminus growth factors, Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate, Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins, May activate FAK and ERK1/ERK2 signaling cascades, May also inhibit neurite outgrowth and growth cone collapse during axon regeneration, May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin, May promote retraction fiber formation and cell polarization through Rho GTPase activation, May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties, May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, extracellular matrix proteases modulating their activity, Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CSPG4, Chondroitin sulfate proteoglycan 4, Chondroitin sulfate proteoglycan NG2, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, Melanoma chondroitin sulfate proteoglycan, Melanoma-associated chondroitin sulfate proteoglycan, NG2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetChondroitin sulfate proteoglycan NG2
Short nameChondroitin sulfate proteoglycan NG2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameChondroitin sulfate proteoglycan NG2 (Antibody to)
Alternative techniqueantibodies
Identity 10068
Gene RNF5
Long gene name ring finger protein 5
Synonyms gene name E3 ubiquitin protein ligase , ring finger protein 5
Synonyms NG2 G16 RING5 RMA1
Locus 6p21, 32
Discovery year 1997-10-16
GenBank acession U89336
Entrez gene record 6048
Pubmed identfication 9533025
RefSeq identity NM_006913
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000031093

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