Name : CHRNA10 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3581358560
| Long name | ALEXA FLUOR 488 Conjugated, CHRNA10 Polyclonal Antibody |
| Also known as | Anti-CHRNA10 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CHRNA10 |
| Specificity | This is a highly specific antibody against CHRNA10 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CHRNA10 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | ACh Ralpha 10, AChR alpha 10 forms a hetero-oligomeric channels in conjunction with AChR alpha 9 and is considered an ionotropic receptor with a probable role in the modulation of auditory stimuli, Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system, Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, These transmembrane receptors change conformation in response to their cognate neurotransmitter, Two important members of this family are the nicotinic acetylcholine and glutamate receptors, allowing ions to move through the pore, also known as CHRNA10, an enzyme that rapidly hydrolyzes acetylcholine, both of which are composed of five homologous subunits forming a transmembrane aqueous pore, cultured T-cells and peripheral blood lymphocytes, immortalized B-cells, is a 450 amino acid multi-pass membrane protein expressed in inner-ear tissue, tonsil, Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CHRNA10 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | CHRNA10 |
| Short name | CHRNA10 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, CHRNA10 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 13800 |
| Gene | CHRNA10 |
| Long gene name | cholinergic receptor nicotinic alpha 10 subunit |
| Synonyms gene name | alpha 10 (neuronal) cholinergic receptor, alpha polypeptide 10 cholinergic receptor, cholinergic receptor, nicotinic, nicotinic, nicotinic alpha 10 |
| Synonyms name | acetylcholine receptor, alpha 10 (neuronal) , nicotinic |
| Locus | 11p15, 4 |
| Discovery year | 2000-11-28 |
| GenBank acession | AF199235 |
| Entrez gene record | 57053 |
| Classification | Cholinergic receptors nicotinic subunits |
| Havana BLAST/BLAT | OTTHUMG00000011844 |