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CHRNA10 Antibody, Biotin Conjugated

CHRNA10 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, CHRNA10 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCHRNA10
SpecificityThis is a highly specific antibody against CHRNA10
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human CHRNA10
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background ACh Ralpha 10, AChR alpha 10 forms a hetero-oligomeric channels in conjunction with AChR alpha 9 and is considered an ionotropic receptor with a probable role in the modulation of auditory stimuli, Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system, Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, These transmembrane receptors change conformation in response to their cognate neurotransmitter, Two important members of this family are the nicotinic acetylcholine and glutamate receptors, allowing ions to move through the pore, also known as CHRNA10, an enzyme that rapidly hydrolyzes acetylcholine, both of which are composed of five homologous subunits forming a transmembrane aqueous pore, cultured T-cells and peripheral blood lymphocytes, immortalized B-cells, is a 450 amino acid multi-pass membrane protein expressed in inner-ear tissue, tonsil, Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCHRNA10 Conjugated
Short name Conjugated, CHRNA10 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, CHRNA10 (Antibody to)
Alternative techniqueantibodies
Identity 13800
Gene CHRNA10
Long gene name cholinergic receptor nicotinic alpha 10 subunit
Synonyms gene name alpha 10 (neuronal) cholinergic receptor, alpha polypeptide 10 cholinergic receptor, cholinergic receptor, nicotinic, nicotinic, nicotinic alpha 10
Synonyms name acetylcholine receptor, alpha 10 (neuronal) , nicotinic
Locus 11p15, 4
Discovery year 2000-11-28
GenBank acession AF199235
Entrez gene record 57053
Classification Cholinergic receptors nicotinic subunits
Havana BLAST/BLAT OTTHUMG00000011844

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