Name : CHRNA3 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9674748317
| Long name | ALEXA FLUOR 488 Conjugated, CHRNA3 Polyclonal Antibody |
| Also known as | Anti-CHRNA3 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CHRNA3 |
| Specificity | This is a highly specific antibody against CHRNA3 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | ±, 3, This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CHRNA3/AChRÎ |
| Gene ID Number | 1136 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | AChR?, Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system, NACHRA3 or CHRNA3, Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, PAOD2, The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, These transmembrane receptors change conformation in response to their cognate neurotransmitter, Two important members of this family are the nicotinic acetylcholine and glutamate receptors, allowing ions to move through the pore, also known as LNCR2, an enzyme that rapidly hydrolyzes acetylcholine, both of which are composed of five homologous subunits forming a transmembrane aqueous pore, is a 505 amino acid multi-pass membrane protein that belongs to the ligand-gated ion channel receptor family and may play a role in neurotransmission, Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CHRNA3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | CHRNA3 |
| Short name | CHRNA3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, CHRNA3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1957 |
| Gene | CHRNA3 |
| Long gene name | cholinergic receptor nicotinic alpha 3 subunit |
| Synonyms gene name | alpha 3 (neuronal) cholinergic receptor, alpha polypeptide 3 cholinergic receptor, cholinergic receptor, nicotinic, nicotinic, nicotinic alpha 3 |
| Synonyms name | acetylcholine receptor, alpha 3 (neuronal) , nicotinic |
| Locus | 15q25, 1 |
| Discovery year | 1990-05-11 |
| Entrez gene record | 1136 |
| Pubmed identfication | 2004777 |
| Classification | Cholinergic receptors nicotinic subunits |
| Havana BLAST/BLAT | OTTHUMG00000143863 |