Name : Chromogranin C/Sg II Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2908797765
| Long name | Chromogranin C/Sg II Primary Polyclonal Antibody |
| Also known as | Chromogranin C/Sg II PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Chromogranin C/Sg II |
| Specificity | This is a highly specific antibody against Chromogranin C/Sg II |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Chromogranin C/Sg II |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Family members include chromogranin A (Chr-A), High levels of Chr-A expression are characteristic of neuroendocrine tumors, In neuroendocrine cells the level Sg II has been shown to increase four-fold in response to histamine, In the anterior lobe of the rat pituitary gland, Pancreastatin exists as two forms, Pancreastatin is a peptide derived from Chr-A which inhibits insulin secretion, Sg III and carboxypeptidase E (CPE) bind specifically to cholesterol-rich secretory granule (SG) membranes, Sg III is an acidic secretory protein expressed in neuronal and endocrine cells, Sg III is present in mammotropes and thyrotropes, also known as secretogranin I, and secretogranin III (Sg III or SCG3), chromogranin B (Chr-B), chromogranin C (also known as secretogranin II or Sg II), exocrine pancreatic secretion and gastric acid secretion, moderately in gonadotropes and corticotropes, neuroendocrine and neuronal tissue, the major form is expressed in stomach and colon extracts, though not in somatotropes, while levels of Chr-A and Chr-B showed little or no increase, Chromogranins (secretogranins) are acidic glycoproteins that localize within secretory granules of endocrine |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Chromogranin-C, MEN1, SCG2, SCG2_HUMAN, SN, Secretogranin II, Secretogranin-2, Secretoneurin, Secretoneurin included, SgII, CHGC |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Chromogranin C/Sg II |
| Short name | Chromogranin C/Sg II Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Chromogranin C/Sg II (Antibody to) |
| Alternative technique | antibodies |