Name : Chromogranin C/Sg II Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN7344933030
| Long name | ALEXA FLUOR 350 Conjugated, Chromogranin C/Sg II Polyclonal Antibody |
| Also known as | Anti-Chromogranin C/Sg II PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Chromogranin C/Sg II |
| Specificity | This is a highly specific antibody against Chromogranin C/Sg II |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Chromogranin C/Sg II |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Family members include chromogranin A (Chr-A), High levels of Chr-A expression are characteristic of neuroendocrine tumors, In neuroendocrine cells the level Sg II has been shown to increase four-fold in response to histamine, In the anterior lobe of the rat pituitary gland, Pancreastatin exists as two forms, Pancreastatin is a peptide derived from Chr-A which inhibits insulin secretion, Sg III and carboxypeptidase E (CPE) bind specifically to cholesterol-rich secretory granule (SG) membranes, Sg III is an acidic secretory protein expressed in neuronal and endocrine cells, Sg III is present in mammotropes and thyrotropes, also known as secretogranin I, and secretogranin III (Sg III or SCG3), chromogranin B (Chr-B), chromogranin C (also known as secretogranin II or Sg II), exocrine pancreatic secretion and gastric acid secretion, moderately in gonadotropes and corticotropes, neuroendocrine and neuronal tissue, the major form is expressed in stomach and colon extracts, though not in somatotropes, while levels of Chr-A and Chr-B showed little or no increase, Chromogranins (secretogranins) are acidic glycoproteins that localize within secretory granules of endocrine |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | Chromogranin-C, MEN1, SCG2, SCG2_HUMAN, SN, Secretogranin II, Secretogranin-2, Secretoneurin, Secretoneurin included, SgII, CHGC |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | Chromogranin C/Sg II |
| Short name | Chromogranin C/Sg II Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, Chromogranin C/Sg II (Antibody to) |
| Alternative technique | antibodies |