Name : Chymase Antibody
Supplier : NJS POLY
Price :406
SKU : GEN8653587543
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Chymase |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Titration of the Chymase antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This Chymase antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID # | 1215 |
| Purity | Antigen affinity |
| Description | Chymase, Chymase is expressed in mast cells and thought to function in the degradation of the extracellular matrix, In the heart and blood vessels, This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1, and regulation of gland secretion, and the generation of vasoactive peptides, extracellular matrix degradation, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II, rather than angiotensin converting enzyme, the regulation of submucosal gland secretion, Chymase is a major secreted protease of mast cells with suspected roles in vasoactive peptide generation |
| Immunogen | Human partial recombinant protein (AA 22-247) was used as the immunogen for this Chymase antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Chymase antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Chymase |
| Short name | Chymase Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Chymase (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2097 |
| Gene | CMA1 |
| Long gene name | chymase 1 |
| Synonyms gene name | chymase 1, mast cell |
| Locus | 14q12 |
| Discovery year | 1991-06-04 |
| Entrez gene record | 1215 |
| Pubmed identfication | 8468056 |
| RefSeq identity | NM_001836 |
| Havana BLAST/BLAT | OTTHUMG00000140181 |