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CIP2A Antibody / KIAA1524

CIP2A Antibody / KIAA1524 size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCIP2A / KIAA1524
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions1-0, 5ug/ml, Western blot: 0
NotesOptimal dilution of the CIP2A antibody should be determined by the researcher
Intented useThis CIP2A antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q8TCG1
PurityAntigen affinity
Description CIP2A deficient mice are viable, Importantly, In accordance with the oncogenic role of CIP2A, It is required for the malignant cellular growth and for in vivo tumor formation, More recently CIP2A has been shown to regulate phosphorylation and activity of many other oncoproteins and to drive malignant cell growth and tumorigenesis in various human cancer types, also known as 'cancerous inhibitor of PP2A' and p90, is a protein that in humans is encoded by the KIAA1524 gene, overexpression promotes Ras-elicited cell growth and transforms immortalized human cells (HEK-TERVs), suggesting that targeting of oncogenic function of CIP2A would not result in serious side-effects, Protein CIP2A
ImmunogenAmino acids EVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIH of human KIAA1524 were used as the immunogen for the CIP2A antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CIP2A antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCIP2A / KIAA1524
Short nameCIP2A Antibody / KIAA1524
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCIP2A (Antibody to) / KIAA1524
Alternative techniqueantibodies
Identity 29302
Gene KIAA1524
Long gene name KIAA1524
Synonyms CIP2A
Synonyms name cancerous inhibitor of protein phosphatase 2A
Locus 3q13, 13
Discovery year 2005-01-24
GenBank acession AB040957
Entrez gene record 57650
Pubmed identfication 10819331 24214971
RefSeq identity NM_020890
Havana BLAST/BLAT OTTHUMG00000159233

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