| Long name | ALEXA FLUOR 350 Conjugated, CITED1 Polyclonal Antibody |
| Also known as | Anti-CITED1 PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CITED1 |
| Specificity | This is a highly specific antibody against CITED1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 150-193/193 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CITED1 |
| Gene ID Number | 4435 |
| Swiss Prot | Q99966 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling, Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner, Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex, Induces transcription from estrogen-responsive promoters and protection against cell death, May play a role in pigmentation of melanocytes, Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex, Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter, Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling, stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300, Transcriptional coactivator of the p300/CBP-mediated trancription complex |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | CITED1 |
| Short name | CITED1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | 1 (Antibody to), ALEXA FLUOR 350, including L-gutamic acid/L-aspartic acid-rich carboxy-terminal domain, Cbp/p300-interacting transactivator |
| Alternative technique | antibodies |
| Alternative to gene target | 1, CITED1 and IDBG-635694 and ENSBTAG00000045925 and 282182, CITED1 and IDBG-76674 and ENSG00000125931 and 4435, Cited1 and IDBG-164976 and ENSMUSG00000051159 and 12705, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006913 and nucleocytoplasmic transport and biological process this GO :0006915 and apoptotic process and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007420 and brain development and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030318 and melanocyte differentiation and biological process this GO :0030511 and positive regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032868 and response to insulin and biological process this GO :0034097 and response to cytokine and biological process this GO :0034341 and response to interferon-gamma and biological process this GO :0042438 and melanin biosynthetic process and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043473 and pigmentation and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043627 and response to estrogen and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045668 and negative regulation of osteoblast differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0050693 and LBD domain binding and molecular function this GO :0051591 and response to cAMP and biological process this GO :0060231 and mesenchymal to epithelial transition and biological process this GO :0060395 and SMAD protein signal transduction and biological process this GO :0060711 and labyrinthine layer development and biological process this GO :0060712 and spongiotrophoblast layer development and biological process this GO :0070410 and co-SMAD binding and molecular function this GO :0070555 and response to interleukin-1 and biological process this GO :0070669 and response to interleukin-2 and biological process this GO :0070670 and response to interleukin-4 and biological process this GO :0070741 and response to interleukin-6 and biological process this GO :0071104 and response to interleukin-9 and biological process this GO :0071105 and response to interleukin-11 and biological process this GO :0071107 and response to parathyroid hormone and biological process this GO :0071559 and response to transforming growth factor beta and biological process, MSG1, co-SMAD binding, nuclei, this GO :0000578 and embryonic axis specification and biological process this GO :0001570 and vasculogenesis and biological process this GO :0001656 and metanephros development and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001890 and placenta development and biological process this GO :0003340 and negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis and biological process this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0003682: chromatin binding, this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003713: transcription coactivator activity and also this GO :0005515: protein binding and also this GO :0008022: protein C-terminus binding and also this GO :0042803: protein homodimerization activity and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0050693: LBD domain binding and also this GO :0070410: co-SMAD binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003713: transcription coactivator activity, this GO :0005515: protein binding, this GO :0008022: protein C-terminus binding, this GO :0042803: protein homodimerization activity, this GO :0044212: transcription regulatory region DNA binding, this GO :0050693: LBD domain binding, this GO :0070410: co-SMAD binding, with Glu/Asp-rich carboxy-terminal domain, Cbp/p300-interacting transactivator |
| Identity | 1986 |
| Gene | CITED1 |
| Long gene name | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 |
| Synonyms gene | MSG1 |
| Synonyms gene name | 1 , Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain |
| Locus | Xq13, 1 |
| Discovery year | 1998-03-27 |
| GenBank acession | U65092 |
| Entrez gene record | 4435 |
| Pubmed identfication | 8901575 9721210 |
| RefSeq identity | NM_004143 |
| Havana BLAST/BLAT | OTTHUMG00000021812 |
| Locus Specific Databases | Mental Retardation database |
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