Name : CK II alpha Antibody, Cy5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN8138181745
| Long name | Cy5 Conjugated, CK II alpha Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CK II alpha |
| Specificity | This is a highly specific antibody against CK II alpha |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 200-250/391 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from human CK II alpha |
| Gene ID number | 1457 |
| Swiss Prot | P68400 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | ATF1, Acts as an ectokinase that phosphorylates several extracellular proteins, Also phosphorylates and regulates numerous transcription factors including NF-kappa-B, Also required for p53/TP53-mediated apoptosis, CMV and HPV, CREB1, Can also negatively regulate apoptosis, During mitosis, During viral infection, FOS, HBV, HCV, HIV, HSV, II, III and IV, IRF1, IRF2, JUN, MAX, MYC and MYB, May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response, Phosphorylates Hsp90 and its co-chaperones FKBP4 and CDC37, Phosphorylates PML at 'Ser-565' and primes it for ubiquitin-mediated degradation, Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3, Phosphorylation protects CASP9 from cleavage and activation by CASP8, Regulates Wnt signaling by phosphorylating CTNNB1 and the transcription factor LEF1, Regulates numerous cellular processes, Regulates transcription by direct phosphorylation of RNA polymerases I, SRF, STAT1, and inhibits the dimerization of CASP2 and activation of CASP8, apoptosis and transcription, as well as viral infection, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage, phosphorylates various proteins involved in the viral life cycles of EBV, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation, such as cell cycle progression, which is essential for chaperone function, Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 625, 650nm/670nm |
| Synonyms | CK II alpha, CK2A1, CSNK2A1, CSNK2A3, Casein kinase II subunit alpha, CKII |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CK II alpha Conjugated |
| Short name | Conjugated, CK II alpha Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy5 |
| Alternative name | cyanine 5 coupled, CK II a (Antibody to) |
| Alternative technique | antibodies |