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CK10 Antibody, Cy5 Conjugated

CK10 Antibody, Cy5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5 Conjugated, CK10 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCK10
Specificity 13, 14, 15, 17 based on an 85% sequence similarity in the immunogen range, This antibody my have secondary cross-reactivities with Keratin 12, This is a highly specific antibody against CK10
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range140-190/584
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human CK10
Gene ID number3858
Swiss ProtP13645
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A number of alleles are known that mainly differ in the Gly-rich region (positions 490-560), AEI resembles clinical and histologic features of both epidermolytic hyperkeratosis and ichthyosis bullosa of Siemens, At birth, Cytokeratin 10 is generally associated with keratin 1, Defects in cytokeratin 10 are a cause of epidermolytic hyperkeratosis (EHK), Defects in cytokeratin 10 are also a cause of annular epidermolytic ichthyosis (AEI), EHK is an hereditary skin disorder characterized by blistering and a marked thickening of the stratum corneum, It is seen in all suprabasal cell layers including stratum corneum, Transmission is autosomal dominant, Within a few weeks, affected individuals usually present with redness, also known as bullous congenital ichthyosiform erythroderma (BCIE) or bullous erythroderma ichthyosiformis congenita of Brocq, also known as cyclic ichthyosis with epidermolytic hyperkeratosis, blisters and superficial erosions due to cytolysis, but most cases are sporadic, the erythroderma and blister formation diminish and hyperkeratoses develop, Cytokeratin 10 is a heterotetramer of two type I and two type II keratins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms K10 CK10
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCK10 Conjugated
Short name Conjugated, CK10 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, CK10 (Antibody to)
Alternative techniqueantibodies
Identity 6413
Gene KRT10
Long gene name keratin 10
Synonyms gene KPP
Synonyms gene name keratosis palmaris et plantaris keratin 10, type I
Synonyms name cytokeratin 10 epidermolytic hyperkeratosis
Locus 17q21, 2
Discovery year 1988-08-12
GenBank acession J04029
Entrez gene record 3858
Pubmed identfication 2461420 16831889
RefSeq identity NM_000421
Classification Keratins, type I
Havana BLAST/BLAT OTTHUMG00000133368

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