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CKIP-1 Antibody

CKIP-1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCKIP-1 Primary Polyclonal Antibody
Also known asCKIP-1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCKIP-1
SpecificityThis is a highly specific antibody against CKIP-1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range60-110/409
Subcellular location Cell membrane, Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CKIP-1
Gene ID number51177
Swiss ProtQ53GL0
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also implicated in PI3K-regulated muscle differentiation, Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival, Appears to target ATM to the plasma membrane, May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2), When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF, Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C-Jun-binding protein, CK2-interacting protein 1, CKIP-1, CKIP1, Casein kinase 2-interacting protein 1, HQ0024c, JBP, OC120, Osteoclast maturation-associated gene 120 protein, PH domain-containing family O member 1, PLEKHO1, Pleckstrin homology domain-containing family O member 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCKIP-1
Short nameCKIP-1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCKIP-1 (Antibody to)
Alternative techniqueantibodies
Identity 24310
Gene PLEKHO1
Long gene name pleckstrin homology domain containing O1
Synonyms gene name family O member 1 , pleckstrin homology domain containing
Synonyms CKIP-1 OC120
Locus 1q21, 2
Discovery year 2005-11-28
GenBank acession AF073836
Entrez gene record 51177
Pubmed identfication 10799509
RefSeq identity NM_016274
Classification Pleckstrin homology domain containing
Havana BLAST/BLAT OTTHUMG00000012510

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